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Does mTORC1 inhibit autophagy at dual stages?: A possible role of mTORC1 in late-stage autophagy inhibition in addition to its known early-stage autophagy inhibition.
Bioessays. 2021 Feb;43(2):e2000187. doi: 10.1002/bies.202000187. Epub 2020 Nov 9.
Bioessays. 2021.
PMID: 33165974
Autophagy inhibition by biotin elicits endoplasmic reticulum stress to differentially regulate adipocyte lipid and protein synthesis.
Selvam S, Ramaian Santhaseela A, Ganesan D, Rajasekaran S, Jayavelu T.
Selvam S, et al. Among authors: ramaian santhaseela a.
Cell Stress Chaperones. 2019 Mar;24(2):343-350. doi: 10.1007/s12192-018-00967-9. Epub 2019 Jan 15.
Cell Stress Chaperones. 2019.
PMID: 30648232
Free PMC article.
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Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA-mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain.
Ganesan D, Ramaian Santhaseela A, Rajasekaran S, Selvam S, Jayavelu T.
Ganesan D, et al. Among authors: ramaian santhaseela a.
J Neurochem. 2020 Sep;154(5):562-575. doi: 10.1111/jnc.14979. Epub 2020 Feb 23.
J Neurochem. 2020.
PMID: 32030764
Free article.
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Altered Lysosomal Function Manipulates Cellular Biosynthetic Capacity By Remodeling Intracellular Cholesterol Distribution.
Rajasekaran S, Ramaian Santhaseela A, Ragunathan S, Venkataraman S, Jayavelu T.
Rajasekaran S, et al. Among authors: ramaian santhaseela a.
Cell Biochem Biophys. 2023 Mar;81(1):29-38. doi: 10.1007/s12013-022-01123-y. Epub 2022 Dec 2.
Cell Biochem Biophys. 2023.
PMID: 36459362
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