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CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion.
Russo GL, Sonsalla G, Natarajan P, Breunig CT, Bulli G, Merl-Pham J, Schmitt S, Giehrl-Schwab J, Giesert F, Jastroch M, Zischka H, Wurst W, Stricker SH, Hauck SM, Masserdotti G, Götz M. Russo GL, et al. Among authors: giehrl schwab j. Cell Stem Cell. 2021 Mar 4;28(3):524-534.e7. doi: 10.1016/j.stem.2020.10.015. Epub 2020 Nov 16. Cell Stem Cell. 2021. PMID: 33202244 Free PMC article.
CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion.
Russo GL, Sonsalla G, Natarajan P, Breunig CT, Bulli G, Merl-Pham J, Schmitt S, Giehrl-Schwab J, Giesert F, Jastroch M, Zischka H, Wurst W, Stricker SH, Hauck SM, Masserdotti G, Götz M. Russo GL, et al. Among authors: giehrl schwab j. Cell Stem Cell. 2021 Mar 4;28(3):584. doi: 10.1016/j.stem.2020.11.017. Cell Stem Cell. 2021. PMID: 33667363 Free PMC article. No abstract available.
Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.
Giehrl-Schwab J, Giesert F, Rauser B, Lao CL, Hembach S, Lefort S, Ibarra IL, Koupourtidou C, Luecken MD, Truong DJ, Fischer-Sternjak J, Masserdotti G, Prakash N, Ninkovic J, Hölter SM, Vogt Weisenhorn DM, Theis FJ, Götz M, Wurst W. Giehrl-Schwab J, et al. EMBO Mol Med. 2022 May 9;14(5):e14797. doi: 10.15252/emmm.202114797. Epub 2022 Apr 4. EMBO Mol Med. 2022. PMID: 35373464 Free PMC article.