Kochanek S - Search Results

1

Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8⁺ T Cell Responses.

Ring SS, Królik M, Hartmann F, Schmidt E, Ali OH, Ludewig B, Kochanek S, Flatz L. Ring SS, et al. Among authors: kochanek s. Mol Ther Oncolytics. 2020 Oct 10;19:179-187. doi: 10.1016/j.omto.2020.10.001. eCollection 2020 Dec 16. Mol Ther Oncolytics. 2020. PMID: 33209978 Free PMC article.

2

Combined genetic and chemical capsid modifications enable flexible and efficient de- and retargeting of adenovirus vectors.

Kreppel F, Gackowski J, Schmidt E, Kochanek S. Kreppel F, et al. Among authors: kochanek s. Mol Ther. 2005 Jul;12(1):107-17. doi: 10.1016/j.ymthe.2005.03.006. Mol Ther. 2005. PMID: 15963926 Free article.

3

High-capacity adenoviral vectors circumvent the limitations of ΔE1 and ΔE1/ΔE3 adenovirus vectors to induce multispecific transgene product-directed CD8 T-cell responses.

Kron MW, Engler T, Schmidt E, Schirmbeck R, Kochanek S, Kreppel F. Kron MW, et al. Among authors: kochanek s. J Gene Med. 2011 Dec;13(12):648-57. doi: 10.1002/jgm.1629. J Gene Med. 2011. PMID: 22095925

4

Modifications of adenovirus hexon allow for either hepatocyte detargeting or targeting with potential evasion from Kupffer cells.

Prill JM, Espenlaub S, Samen U, Engler T, Schmidt E, Vetrini F, Rosewell A, Grove N, Palmer D, Ng P, Kochanek S, Kreppel F. Prill JM, et al. Among authors: kochanek s. Mol Ther. 2011 Jan;19(1):83-92. doi: 10.1038/mt.2010.229. Epub 2010 Oct 19. Mol Ther. 2011. PMID: 20959811 Free PMC article.

5

Recombinant complexes of antigen with stress proteins are potent CD8 T-cell-stimulating immunogens.

Wieland A, Denzel M, Schmidt E, Kochanek S, Kreppel F, Reimann J, Schirmbeck R. Wieland A, et al. Among authors: kochanek s. J Mol Med (Berl). 2008 Sep;86(9):1067-79. doi: 10.1007/s00109-008-0371-x. Epub 2008 Jun 13. J Mol Med (Berl). 2008. PMID: 18551265

6

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.

Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Kochanek S, Broek Mv, Radbruch A, Lévy F, Lambert PH, Siegrist CA, Restifo NP, Löhning M, Ochsenbein AF, Nabel GJ, Pinschewer DD. Flatz L, et al. Among authors: kochanek s. Nat Med. 2010 Mar;16(3):339-45. doi: 10.1038/nm.2104. Epub 2010 Feb 7. Nat Med. 2010. PMID: 20139992 Free PMC article.

7

Evaluation of life cycle defective adenovirus mutants for production of adeno-associated virus vectors.

Krüger-Haag A, Lehmann C, Schmidt E, Sonntag F, Hörer M, Kochanek S. Krüger-Haag A, et al. Among authors: kochanek s. J Gene Med. 2019 Jun;21(6):e3094. doi: 10.1002/jgm.3094. Epub 2019 May 28. J Gene Med. 2019. PMID: 31037799

8

miRNA-mediated silencing in hepatocytes can increase adaptive immune responses to adenovirus vector-delivered transgenic antigens.

Kron MW, Espenlaub S, Engler T, Schirmbeck R, Kochanek S, Kreppel F. Kron MW, et al. Among authors: kochanek s. Mol Ther. 2011 Aug;19(8):1547-57. doi: 10.1038/mt.2011.83. Epub 2011 May 10. Mol Ther. 2011. PMID: 21556053 Free PMC article.

9

Fully detargeted polyethylene glycol-coated adenovirus vectors are potent genetic vaccines and escape from pre-existing anti-adenovirus antibodies.

Wortmann A, Vöhringer S, Engler T, Corjon S, Schirmbeck R, Reimann J, Kochanek S, Kreppel F. Wortmann A, et al. Among authors: kochanek s. Mol Ther. 2008 Jan;16(1):154-62. doi: 10.1038/sj.mt.6300306. Epub 2007 Sep 11. Mol Ther. 2008. PMID: 17848961 Free article.

10

The immunogenicity of adenovirus vectors limits the multispecificity of CD8 T-cell responses to vector-encoded transgenic antigens.

Schirmbeck R, Reimann J, Kochanek S, Kreppel F. Schirmbeck R, et al. Among authors: kochanek s. Mol Ther. 2008 Sep;16(9):1609-16. doi: 10.1038/mt.2008.141. Epub 2008 Jul 8. Mol Ther. 2008. PMID: 18612271 Free article.

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