Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

17 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Discovery of Potent and Selective 7-Azaindole Isoindolinone-Based PI3Kγ Inhibitors.
Miles DH, Yan X, Thomas-Tran R, Fournier J, Sharif EU, Drew SL, Mata G, Lawson KV, Ginn E, Wong K, Soni D, Dhanota P, Shaqfeh SG, Meleza C, Chen A, Pham AT, Park T, Swinarski D, Banuelos J, Schindler U, Walters MJ, Walker NP, Zhao X, Young SW, Chen J, Jin L, Leleti MR, Powers JP, Jeffrey JL. Miles DH, et al. Among authors: lawson kv. ACS Med Chem Lett. 2020 Sep 24;11(11):2244-2252. doi: 10.1021/acsmedchemlett.0c00387. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214836 Free PMC article.
Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73.
Beatty JW, Lindsey EA, Thomas-Tran R, Debien L, Mandal D, Jeffrey JL, Tran AT, Fournier J, Jacob SD, Yan X, Drew SL, Ginn E, Chen A, Pham AT, Zhao S, Jin L, Young SW, Walker NP, Leleti MR, Moschütz S, Sträter N, Powers JP, Lawson KV. Beatty JW, et al. Among authors: lawson kv. J Med Chem. 2020 Apr 23;63(8):3935-3955. doi: 10.1021/acs.jmedchem.9b01713. Epub 2020 Apr 8. J Med Chem. 2020. PMID: 32212732
Discovery of AB680: A Potent and Selective Inhibitor of CD73.
Lawson KV, Kalisiak J, Lindsey EA, Newcomb ET, Leleti MR, Debien L, Rosen BR, Miles DH, Sharif EU, Jeffrey JL, Tan JBL, Chen A, Zhao S, Xu G, Fu L, Jin L, Park TW, Berry W, Moschütz S, Scaletti E, Sträter N, Walker NP, Young SW, Walters MJ, Schindler U, Powers JP. Lawson KV, et al. J Med Chem. 2020 Oct 22;63(20):11448-11468. doi: 10.1021/acs.jmedchem.0c00525. Epub 2020 Jul 20. J Med Chem. 2020. PMID: 32614585
Discovery of Potent and Selective PI3Kγ Inhibitors.
Drew SL, Thomas-Tran R, Beatty JW, Fournier J, Lawson KV, Miles DH, Mata G, Sharif EU, Yan X, Mailyan AK, Ginn E, Chen J, Wong K, Soni D, Dhanota P, Chen PY, Shaqfeh SG, Meleza C, Pham AT, Chen A, Zhao X, Banuelos J, Jin L, Schindler U, Walters MJ, Young SW, Walker NP, Leleti MR, Powers JP, Jeffrey JL. Drew SL, et al. Among authors: lawson kv. J Med Chem. 2020 Oct 8;63(19):11235-11257. doi: 10.1021/acs.jmedchem.0c01203. Epub 2020 Sep 16. J Med Chem. 2020. PMID: 32865410 Free article.
Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors.
Sharif EU, Kalisiak J, Lawson KV, Miles DH, Newcomb E, Lindsey EA, Rosen BR, Debien LPP, Chen A, Zhao X, Young SW, Walker NP, Sträter N, Scaletti ER, Jin L, Xu G, Leleti MR, Powers JP. Sharif EU, et al. Among authors: lawson kv. J Med Chem. 2021 Jan 14;64(1):845-860. doi: 10.1021/acs.jmedchem.0c01835. Epub 2021 Jan 5. J Med Chem. 2021. PMID: 33399453
Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ).
Mata G, Miles DH, Drew SL, Fournier J, Lawson KV, Mailyan AK, Sharif EU, Yan X, Beatty JW, Banuelos J, Chen J, Ginn E, Chen A, Gerrick KY, Pham AT, Wong K, Soni D, Dhanota P, Shaqfeh SG, Meleza C, Narasappa N, Singh H, Zhao X, Jin L, Schindler U, Walters MJ, Young SW, Walker NP, Leleti MR, Powers JP, Jeffrey JL. Mata G, et al. Among authors: lawson kv. J Med Chem. 2022 Jan 27;65(2):1418-1444. doi: 10.1021/acs.jmedchem.1c01153. Epub 2021 Oct 21. J Med Chem. 2022. PMID: 34672584
17 results