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Page 1
Discovery of Potent and Selective 7-Azaindole Isoindolinone-Based PI3Kγ Inhibitors.
Miles DH, Yan X, Thomas-Tran R, Fournier J, Sharif EU, Drew SL, Mata G, Lawson KV, Ginn E, Wong K, Soni D, Dhanota P, Shaqfeh SG, Meleza C, Chen A, Pham AT, Park T, Swinarski D, Banuelos J, Schindler U, Walters MJ, Walker NP, Zhao X, Young SW, Chen J, Jin L, Leleti MR, Powers JP, Jeffrey JL. Miles DH, et al. Among authors: schindler u. ACS Med Chem Lett. 2020 Sep 24;11(11):2244-2252. doi: 10.1021/acsmedchemlett.0c00387. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214836 Free PMC article.
Discovery of Potent and Selective PI3Kγ Inhibitors.
Drew SL, Thomas-Tran R, Beatty JW, Fournier J, Lawson KV, Miles DH, Mata G, Sharif EU, Yan X, Mailyan AK, Ginn E, Chen J, Wong K, Soni D, Dhanota P, Chen PY, Shaqfeh SG, Meleza C, Pham AT, Chen A, Zhao X, Banuelos J, Jin L, Schindler U, Walters MJ, Young SW, Walker NP, Leleti MR, Powers JP, Jeffrey JL. Drew SL, et al. Among authors: schindler u. J Med Chem. 2020 Oct 8;63(19):11235-11257. doi: 10.1021/acs.jmedchem.0c01203. Epub 2020 Sep 16. J Med Chem. 2020. PMID: 32865410 Free article.
Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ).
Mata G, Miles DH, Drew SL, Fournier J, Lawson KV, Mailyan AK, Sharif EU, Yan X, Beatty JW, Banuelos J, Chen J, Ginn E, Chen A, Gerrick KY, Pham AT, Wong K, Soni D, Dhanota P, Shaqfeh SG, Meleza C, Narasappa N, Singh H, Zhao X, Jin L, Schindler U, Walters MJ, Young SW, Walker NP, Leleti MR, Powers JP, Jeffrey JL. Mata G, et al. Among authors: schindler u. J Med Chem. 2022 Jan 27;65(2):1418-1444. doi: 10.1021/acs.jmedchem.1c01153. Epub 2021 Oct 21. J Med Chem. 2022. PMID: 34672584
Journal Production Guidance for Software and Data Citations.
Stall S, Bilder G, Cannon M, Chue Hong N, Edmunds S, Erdmann CC, Evans M, Farmer R, Feeney P, Friedman M, Giampoala M, Hanson RB, Harrison M, Karaiskos D, Katz DS, Letizia V, Lizzi V, MacCallum C, Muench A, Perry K, Ratner H, Schindler U, Sedora B, Stockhause M, Townsend R, Yeston J, Clark T. Stall S, et al. Among authors: schindler u. Sci Data. 2023 Sep 26;10(1):656. doi: 10.1038/s41597-023-02491-7. Sci Data. 2023. PMID: 37752153 Free PMC article.
PANGAEA - Data Publisher for Earth & Environmental Science.
Felden J, Möller L, Schindler U, Huber R, Schumacher S, Koppe R, Diepenbroek M, Glöckner FO. Felden J, et al. Among authors: schindler u. Sci Data. 2023 Jun 2;10(1):347. doi: 10.1038/s41597-023-02269-x. Sci Data. 2023. PMID: 37268655 Free PMC article.
Impact of the selective A2AR and A2BR dual antagonist AB928/etrumadenant on CAR T cell function.
Seifert M, Benmebarek MR, Briukhovetska D, Märkl F, Dörr J, Cadilha BL, Jobst J, Stock S, Andreu-Sanz D, Lorenzini T, Grünmeier R, Oner A, Obeck H, Majed L, Dhoqina D, Feinendegen M, Gottschlich A, Zhang J, Schindler U, Endres S, Kobold S. Seifert M, et al. Among authors: schindler u. Br J Cancer. 2022 Dec;127(12):2175-2185. doi: 10.1038/s41416-022-02013-z. Epub 2022 Oct 20. Br J Cancer. 2022. PMID: 36266575 Free PMC article.
Targeting CD73 with AB680 (Quemliclustat), a Novel and Potent Small-Molecule CD73 Inhibitor, Restores Immune Functionality and Facilitates Antitumor Immunity.
Piovesan D, Tan JBL, Becker A, Banuelos J, Narasappa N, DiRenzo D, Zhang K, Chen A, Ginn E, Udyavar AR, Yin F, Paprcka SL, Purandare B, Park TW, Kimura N, Kalisiak J, Young SW, Powers JP, Schindler U, Sivick KE, Walters MJ. Piovesan D, et al. Among authors: schindler u. Mol Cancer Ther. 2022 Jun 1;21(6):948-959. doi: 10.1158/1535-7163.MCT-21-0802. Mol Cancer Ther. 2022. PMID: 35405741 Free PMC article.
Discovery of AB680: A Potent and Selective Inhibitor of CD73.
Lawson KV, Kalisiak J, Lindsey EA, Newcomb ET, Leleti MR, Debien L, Rosen BR, Miles DH, Sharif EU, Jeffrey JL, Tan JBL, Chen A, Zhao S, Xu G, Fu L, Jin L, Park TW, Berry W, Moschütz S, Scaletti E, Sträter N, Walker NP, Young SW, Walters MJ, Schindler U, Powers JP. Lawson KV, et al. Among authors: schindler u. J Med Chem. 2020 Oct 22;63(20):11448-11468. doi: 10.1021/acs.jmedchem.0c00525. Epub 2020 Jul 20. J Med Chem. 2020. PMID: 32614585
Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: design and initial results of the Fr1da study.
Raab J, Haupt F, Scholz M, Matzke C, Warncke K, Lange K, Assfalg R, Weininger K, Wittich S, Löbner S, Beyerlein A, Nennstiel-Ratzel U, Lang M, Laub O, Dunstheimer D, Bonifacio E, Achenbach P, Winkler C, Ziegler AG; Fr1da Study Group. Raab J, et al. BMJ Open. 2016 May 18;6(5):e011144. doi: 10.1136/bmjopen-2016-011144. BMJ Open. 2016. PMID: 27194320 Free PMC article.
75 results