Johnson KJ - Search Results

1

A rat subchronic study transcriptional point of departure estimates a carcinogenicity study apical point of departure.

Bianchi E, Costa E, Yan ZJ, Murphy L, Howell J, Anderson D, Mukerji P, Venkatraman A, Terry C, Johnson KJ. Bianchi E, et al. Among authors: johnson kj. Food Chem Toxicol. 2021 Jan;147:111869. doi: 10.1016/j.fct.2020.111869. Epub 2020 Nov 18. Food Chem Toxicol. 2021. PMID: 33217531 Free article.

2

Dose-response analysis of epigenetic, metabolic, and apical endpoints after short-term exposure to experimental hepatotoxicants.

Miousse IR, Murphy LA, Lin H, Schisler MR, Sun J, Chalbot MG, Sura R, Johnson K, LeBaron MJ, Kavouras IG, Schnackenberg LK, Beger RD, Rasoulpour RJ, Koturbash I. Miousse IR, et al. Food Chem Toxicol. 2017 Nov;109(Pt 1):690-702. doi: 10.1016/j.fct.2017.05.013. Epub 2017 May 8. Food Chem Toxicol. 2017. PMID: 28495587 Free PMC article.

3

Short-term toxicogenomics as an alternative approach to chronic in vivo studies for derivation of points of departure: A case study in the rat with a triazole fungicide.

LaRocca J, Costa E, Sriram S, Hannas BR, Johnson KJ. LaRocca J, et al. Among authors: johnson kj. Regul Toxicol Pharmacol. 2020 Jun;113:104655. doi: 10.1016/j.yrtph.2020.104655. Epub 2020 Apr 5. Regul Toxicol Pharmacol. 2020. PMID: 32268158

4

A Rat Liver Transcriptomic Point of Departure Predicts a Prospective Liver or Non-liver Apical Point of Departure.

Johnson KJ, Auerbach SS, Costa E. Johnson KJ, et al. Toxicol Sci. 2020 Jul 1;176(1):86-102. doi: 10.1093/toxsci/kfaa062. Toxicol Sci. 2020. PMID: 32384157 Free PMC article.

5

Bridging Sex-Specific Differences in the CAR-Mediated Hepatocarcinogenesis of Nitrapyrin Using Molecular and Apical Endpoints.

Murphy L, LeBaron MJ, Johnson K, Rasoulpour RJ, Wang X, LaRocca J. Murphy L, et al. Front Toxicol. 2021 Oct 29;3:766196. doi: 10.3389/ftox.2021.766196. eCollection 2021. Front Toxicol. 2021. PMID: 35295143 Free PMC article.

6

A microRNA or messenger RNA point of departure estimates an apical endpoint point of departure in a rat developmental toxicity model.

Johnson KJ, Costa E, Marshall V, Sriram S, Venkatraman A, Stebbins K, LaRocca J. Johnson KJ, et al. Birth Defects Res. 2022 Jul 1;114(11):559-576. doi: 10.1002/bdr2.2046. Epub 2022 May 21. Birth Defects Res. 2022. PMID: 35596682 Free PMC article.

7

A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm.

Johnson KJ, Auerbach SS, Stevens T, Barton-Maclaren TS, Costa E, Currie RA, Dalmas Wilk D, Haq S, Rager JE, Reardon AJF, Wehmas L, Williams A, O'Brien J, Yauk C, LaRocca JL, Pettit S. Johnson KJ, et al. Toxicol Sci. 2022 Nov 23;190(2):127-132. doi: 10.1093/toxsci/kfac097. Toxicol Sci. 2022. PMID: 36165699 Free PMC article.

8

From Pipeline to Plant Protection Products: Using New Approach Methodologies (NAMs) in Agrochemical Safety Assessment.

Henriquez JE, Badwaik VD, Bianchi E, Chen W, Corvaro M, LaRocca J, Lunsman TD, Zu C, Johnson KJ. Henriquez JE, et al. Among authors: johnson kj. J Agric Food Chem. 2024 May 15;72(19):10710-10724. doi: 10.1021/acs.jafc.4c00958. Epub 2024 Apr 30. J Agric Food Chem. 2024. PMID: 38688008 Review.

9

Transcriptomic point of departure determination: a comparison of distribution-based and gene set-based approaches.

Costa E, Johnson KJ, Walker CA, O'Brien JM. Costa E, et al. Among authors: johnson kj. Front Genet. 2024 May 9;15:1374791. doi: 10.3389/fgene.2024.1374791. eCollection 2024. Front Genet. 2024. PMID: 38784034 Free PMC article.

10

Bioinformatic Workflows for Deriving Transcriptomic Points of Departure: Current status, Data Gaps, and Research Priorities.

O'Brien J, Mitchell C, Auerbach S, Doonan L, Ewald J, Everett L, Faranda A, Johnson K, Reardon A, Rooney J, Shao K, Stainforth R, Wheeler M, Dalmas Wilk D, Williams A, Yauk C, Costa E. O'Brien J, et al. Toxicol Sci. 2024 Nov 5:kfae145. doi: 10.1093/toxsci/kfae145. Online ahead of print. Toxicol Sci. 2024. PMID: 39499193

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