Hughes D - Search Results

1

Mutant RNA polymerase can reduce susceptibility to antibiotics via ppGpp-independent induction of a stringent-like response.

Brandis G, Granström S, Leber AT, Bartke K, Garoff L, Cao S, Huseby DL, Hughes D. Brandis G, et al. Among authors: hughes d. J Antimicrob Chemother. 2021 Feb 11;76(3):606-615. doi: 10.1093/jac/dkaa469. J Antimicrob Chemother. 2021. PMID: 33221850 Free PMC article.

2

Fusidic acid-resistant EF-G perturbs the accumulation of ppGpp.

Macvanin M, Johanson U, Ehrenberg M, Hughes D. Macvanin M, et al. Among authors: hughes d. Mol Microbiol. 2000 Jul;37(1):98-107. doi: 10.1046/j.1365-2958.2000.01967.x. Mol Microbiol. 2000. PMID: 10931308 Free article.

3

Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.

Komp Lindgren P, Karlsson A, Hughes D. Komp Lindgren P, et al. Among authors: hughes d. Antimicrob Agents Chemother. 2003 Oct;47(10):3222-32. doi: 10.1128/AAC.47.10.3222-3232.2003. Antimicrob Agents Chemother. 2003. PMID: 14506034 Free PMC article.

4

Fusidic acid-resistant mutants of Salmonella enterica serovar Typhimurium with low fitness in vivo are defective in RpoS induction.

Macvanin M, Björkman J, Eriksson S, Rhen M, Andersson DI, Hughes D. Macvanin M, et al. Among authors: hughes d. Antimicrob Agents Chemother. 2003 Dec;47(12):3743-9. doi: 10.1128/AAC.47.12.3743-3749.2003. Antimicrob Agents Chemother. 2003. PMID: 14638476 Free PMC article.

5

Fusidic acid-resistant mutants of Salmonella enterica serovar typhimurium have low levels of heme and a reduced rate of respiration and are sensitive to oxidative stress.

Macvanin M, Ballagi A, Hughes D. Macvanin M, et al. Among authors: hughes d. Antimicrob Agents Chemother. 2004 Oct;48(10):3877-83. doi: 10.1128/AAC.48.10.3877-3883.2004. Antimicrob Agents Chemother. 2004. PMID: 15388448 Free PMC article.

6

Mutant prevention concentrations of ciprofloxacin for urinary tract infection isolates of Escherichia coli.

Marcusson LL, Olofsson SK, Komp Lindgren P, Cars O, Hughes D. Marcusson LL, et al. Among authors: hughes d. J Antimicrob Chemother. 2005 Jun;55(6):938-43. doi: 10.1093/jac/dki136. Epub 2005 Apr 28. J Antimicrob Chemother. 2005. PMID: 15860549

7

Biological cost of single and multiple norfloxacin resistance mutations in Escherichia coli implicated in urinary tract infections.

Komp Lindgren P, Marcusson LL, Sandvang D, Frimodt-Møller N, Hughes D. Komp Lindgren P, et al. Among authors: hughes d. Antimicrob Agents Chemother. 2005 Jun;49(6):2343-51. doi: 10.1128/AAC.49.6.2343-2351.2005. Antimicrob Agents Chemother. 2005. PMID: 15917531 Free PMC article.

8

Selection of ciprofloxacin resistance in Escherichia coli in an in vitro kinetic model: relation between drug exposure and mutant prevention concentration.

Olofsson SK, Marcusson LL, Komp Lindgren P, Hughes D, Cars O. Olofsson SK, et al. Among authors: hughes d. J Antimicrob Chemother. 2006 Jun;57(6):1116-21. doi: 10.1093/jac/dkl135. Epub 2006 Apr 19. J Antimicrob Chemother. 2006. PMID: 16624874

9

Weak mutators can drive the evolution of fluoroquinolone resistance in Escherichia coli.

Orlén H, Hughes D. Orlén H, et al. Among authors: hughes d. Antimicrob Agents Chemother. 2006 Oct;50(10):3454-6. doi: 10.1128/AAC.00783-06. Antimicrob Agents Chemother. 2006. PMID: 17005830 Free PMC article.

10

Dose-related selection of fluoroquinolone-resistant Escherichia coli.

Olofsson SK, Marcusson LL, Strömbäck A, Hughes D, Cars O. Olofsson SK, et al. Among authors: hughes d. J Antimicrob Chemother. 2007 Oct;60(4):795-801. doi: 10.1093/jac/dkm265. Epub 2007 Jul 16. J Antimicrob Chemother. 2007. PMID: 17635875

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