Ruan H - Search Results

1

Integrative structural modeling of a multidomain polo-like kinase.

Ruan H , Kiselar J , Zhang W , Li S , Xiong R , Liu Y , Yang S , Lai L . Ruan H , et al. Phys Chem Chem Phys. 2020 Dec 16;22(47):27581-27589. doi: 10.1039/d0cp05030j. Phys Chem Chem Phys. 2020. PMID: 33236741

2

Herb-target interaction network analysis helps to disclose molecular mechanism of traditional Chinese medicine.

Liang H, Ruan H, Ouyang Q, Lai L. Liang H, et al. Among authors: ruan h. Sci Rep. 2016 Nov 11;6:36767. doi: 10.1038/srep36767. Sci Rep. 2016. PMID: 27833111 Free PMC article.

3

Origin of the Reflectin Gene and Hierarchical Assembly of Its Protein.

Guan Z, Cai T, Liu Z, Dou Y, Hu X, Zhang P, Sun X, Li H, Kuang Y, Zhai Q, Ruan H, Li X, Li Z, Zhu Q, Mai J, Wang Q, Lai L, Ji J, Liu H, Xia B, Jiang T, Luo SJ, Wang HW, Xie C. Guan Z, et al. Among authors: ruan h. Curr Biol. 2017 Sep 25;27(18):2833-2842.e6. doi: 10.1016/j.cub.2017.07.061. Epub 2017 Sep 7. Curr Biol. 2017. PMID: 28889973 Free article.

4

Arabidopsis pollen tube integrity and sperm release are regulated by RALF-mediated signaling.

Ge Z, Bergonci T, Zhao Y, Zou Y, Du S, Liu MC, Luo X, Ruan H, García-Valencia LE, Zhong S, Hou S, Huang Q, Lai L, Moura DS, Gu H, Dong J, Wu HM, Dresselhaus T, Xiao J, Cheung AY, Qu LJ. Ge Z, et al. Among authors: ruan h. Science. 2017 Dec 22;358(6370):1596-1600. doi: 10.1126/science.aao3642. Epub 2017 Dec 14. Science. 2017. PMID: 29242234 Free PMC article.

5

Targeting intrinsically disordered proteins at the edge of chaos.

Ruan H, Sun Q, Zhang W, Liu Y, Lai L. Ruan H, et al. Drug Discov Today. 2019 Jan;24(1):217-227. doi: 10.1016/j.drudis.2018.09.017. Epub 2018 Sep 29. Drug Discov Today. 2019. PMID: 30278223 Review.

6

Computational strategy for intrinsically disordered protein ligand design leads to the discovery of p53 transactivation domain I binding compounds that activate the p53 pathway.

Ruan H, Yu C, Niu X, Zhang W, Liu H, Chen L, Xiong R, Sun Q, Jin C, Liu Y, Lai L. Ruan H, et al. Chem Sci. 2020 Dec 28;12(8):3004-3016. doi: 10.1039/d0sc04670a. Chem Sci. 2020. PMID: 34164069 Free PMC article.

7

Mapping Full Conformational Transition Dynamics of Intrinsically Disordered Proteins Using a Single-Molecule Nanocircuit.

Yin D, Xiong R, Yang Z, Feng J, Liu W, Li S, Li M, Ruan H, Li J, Li L, Lai L, Guo X. Yin D, et al. Among authors: ruan h. ACS Nano. 2024 Sep 14. doi: 10.1021/acsnano.4c04064. Online ahead of print. ACS Nano. 2024. PMID: 39276130

8

More is simpler: Decomposition of ligand-binding affinity for proteins being disordered.

Wang X, Chong B, Sun Z, Ruan H, Yang Y, Song P, Liu Z. Wang X, et al. Among authors: ruan h. Protein Sci. 2022 Jul;31(7):e4375. doi: 10.1002/pro.4375. Protein Sci. 2022. PMID: 35762723 Free PMC article.

9

Effects of stress hyperglycemia ratio upon long-lasting prognosis in coronary artery disease patients with or lacking chronic renal impairment: findings from a Chinese multi-center observational study.

Wu J, Liu J, Yuan Z, Tang S, Zhang W, Xiang Y, Chen J, Lin Q, Guo W, He Y, Huang H, Lu X, Deng J, Ruan H, Jiang R, Chen S, Liu Y. Wu J, et al. Among authors: ruan h. Diabetol Metab Syndr. 2024 Dec 31;16(1):316. doi: 10.1186/s13098-024-01521-7. Diabetol Metab Syndr. 2024. PMID: 39741358 Free PMC article.

10

An animal model recapitulates human hepatic diseases associated with GATA6 mutations.

Shi W, Yi X, Ruan H, Wang D, Wu D, Jiang P, Luo L, Ma X, Jiang F, Li C, Wu W, Luo L, Li L, Wang G, Qiu J, Huang H. Shi W, et al. Among authors: ruan h. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2317801121. doi: 10.1073/pnas.2317801121. Epub 2024 Dec 31. Proc Natl Acad Sci U S A. 2025. PMID: 39739787

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