Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

100 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Towards a mechanism-based approach for the prediction of nongenotoxic carcinogenic potential of agrochemicals.
Heusinkveld H, Braakhuis H, Gommans R, Botham P, Corvaro M, van der Laan JW, Lewis D, Madia F, Manou I, Schorsch F, Wolterink G, Woutersen R, Corvi R, Mehta J, Luijten M. Heusinkveld H, et al. Among authors: botham p. Crit Rev Toxicol. 2020 Oct;50(9):725-739. doi: 10.1080/10408444.2020.1841732. Epub 2020 Nov 25. Crit Rev Toxicol. 2020. PMID: 33236972 Review.
Finding synergies for the 3Rs - Repeated Dose Toxicity testing: Report from an EPAA Partners' Forum.
Laroche C, Annys E, Bender H, Botelho D, Botham P, Brendler-Schwaab S, Clayton R, Corvaro M, Dal Negro G, Delannois F, Dent M, Desaintes C, Desprez B, Dhalluin S, Hartmann A, Hoffmann-Doerr S, Hubesch B, Irizar A, Manou I, Müller BP, Nadzialek S, Prieto P, Rasenberg M, Roggeband R, Rowan TG, Schutte K, van de Water B, Westmoreland C, Whelan M, Wilschut A, Zvonimir Z, Cronin MTD. Laroche C, et al. Among authors: botham p. Regul Toxicol Pharmacol. 2019 Nov;108:104470. doi: 10.1016/j.yrtph.2019.104470. Epub 2019 Aug 31. Regul Toxicol Pharmacol. 2019. PMID: 31479718 Free article.
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?
Marty S, Beekhuijzen M, Charlton A, Hallmark N, Hannas BR, Jacobi S, Melching-Kollmuss S, Sauer UG, Sheets LP, Strauss V, Urbisch D, Botham PA, van Ravenzwaay B. Marty S, et al. Among authors: botham pa. Crit Rev Toxicol. 2021 Apr;51(4):328-358. doi: 10.1080/10408444.2021.1910625. Epub 2021 Jun 2. Crit Rev Toxicol. 2021. PMID: 34074207 Review.
Toward a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part I: which parameters from human studies are most relevant for toxicological assessments?
Sauer UG, Asiimwe A, Botham PA, Charlton A, Hallmark N, Jacobi S, Marty S, Melching-Kollmuss S, Palha JA, Strauss V, van Ravenzwaay B, Swaen G. Sauer UG, et al. Crit Rev Toxicol. 2020 Oct;50(9):740-763. doi: 10.1080/10408444.2020.1839380. Epub 2020 Dec 11. Crit Rev Toxicol. 2020. PMID: 33305658 Review.
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment.
Najjar A, Punt A, Wambaugh J, Paini A, Ellison C, Fragki S, Bianchi E, Zhang F, Westerhout J, Mueller D, Li H, Shi Q, Gant TW, Botham P, Bars R, Piersma A, van Ravenzwaay B, Kramer NI. Najjar A, et al. Among authors: botham p. Arch Toxicol. 2022 Dec;96(12):3407-3419. doi: 10.1007/s00204-022-03356-5. Epub 2022 Sep 5. Arch Toxicol. 2022. PMID: 36063173 Free PMC article.
Integration of paraquat pharmacokinetic data across species using PBPK modelling.
Campbell JL Jr, Travis KZ, Clewell HJ 3rd, Stevens AJ, Hinderliter PM, Andersen ME, Botham PA, Cook AR, Minnema DJ, Wolf DC. Campbell JL Jr, et al. Toxicol Appl Pharmacol. 2021 Apr 15;417:115462. doi: 10.1016/j.taap.2021.115462. Epub 2021 Feb 22. Toxicol Appl Pharmacol. 2021. PMID: 33631233 Free article.
100 results