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Evaluation of bovine milk extracellular vesicles for the delivery of locked nucleic acid antisense oligonucleotides.
Grossen P, Portmann M, Koller E, Duschmalé M, Minz T, Sewing S, Pandya NJ, van Geijtenbeek SK, Ducret A, Kusznir EA, Huber S, Berrera M, Lauer ME, Ringler P, Nordbo B, Jensen ML, Sladojevich F, Jagasia R, Alex R, Gamboni R, Keller M. Grossen P, et al. Among authors: jagasia r. Eur J Pharm Biopharm. 2021 Jan;158:198-210. doi: 10.1016/j.ejpb.2020.11.012. Epub 2020 Nov 26. Eur J Pharm Biopharm. 2021. PMID: 33248268
Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct.
Gehrlein A, Udayar V, Anastasi N, Morella ML, Ruf I, Brugger D, von der Mark S, Thoma R, Rufer A, Heer D, Pfahler N, Jochner A, Niewoehner J, Wolf L, Fueth M, Ebeling M, Villaseñor R, Zhu Y, Deen MC, Shan X, Ehsaei Z, Taylor V, Sidransky E, Vocadlo DJ, Freskgård PO, Jagasia R. Gehrlein A, et al. Among authors: jagasia r. Nat Commun. 2023 Apr 12;14(1):2057. doi: 10.1038/s41467-023-37632-4. Nat Commun. 2023. PMID: 37045813 Free PMC article.
Generation of a homozygous GBA deletion human embryonic stem cell line.
Gündner AL, Meyer CA, Aigner S, Christensen K, Patsch C, Jagasia R, Baumann K, Burcin M. Gündner AL, et al. Among authors: jagasia r. Stem Cell Res. 2017 Aug;23:122-126. doi: 10.1016/j.scr.2017.07.009. Epub 2017 Jul 11. Stem Cell Res. 2017. PMID: 28925361 Free article.
A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells.
Deen MC, Zhu Y, Gros C, Na N, Gilormini PA, Shen DL, Bhosale S, Anastasi N, Wang R, Shan X, Harde E, Jagasia R, Lynn FC, Vocadlo DJ. Deen MC, et al. Among authors: jagasia r. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2200553119. doi: 10.1073/pnas.2200553119. Epub 2022 Jul 12. Proc Natl Acad Sci U S A. 2022. PMID: 35858317 Free PMC article.
Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis.
Lugert S, Kremer T, Jagasia R, Herrmann A, Aigner S, Giachino C, Mendez-David I, Gardier AM, Carralot JP, Meistermann H, Augustin A, Saxe MD, Lamerz J, Duran-Pacheco G, Ducret A, Taylor V, David DJ, Czech C. Lugert S, et al. Among authors: jagasia r. Sci Rep. 2017 Apr 25;7:46543. doi: 10.1038/srep46543. Sci Rep. 2017. PMID: 28440309 Free PMC article.
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology.
Pandya NJ, Wang C, Costa V, Lopatta P, Meier S, Zampeta FI, Punt AM, Mientjes E, Grossen P, Distler T, Tzouros M, Martí Y, Banfai B, Patsch C, Rasmussen S, Hoener M, Berrera M, Kremer T, Dunkley T, Ebeling M, Distel B, Elgersma Y, Jagasia R. Pandya NJ, et al. Among authors: jagasia r. Cell Rep Med. 2021 Aug 17;2(8):100360. doi: 10.1016/j.xcrm.2021.100360. eCollection 2021 Aug 17. Cell Rep Med. 2021. PMID: 34467244 Free PMC article.
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