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Muscarinic agonists inhibit the ATP-dependent potassium current and suppress the ventricle-Purkinje action potential dispersion.
Magyar T, Árpádffy-Lovas T, Pászti B, Tóth N, Szlovák J, Gazdag P, Kohajda Z, Gyökeres A, Györe B, Gurabi Z, Jost N, Virág L, Papp JG, Nagy N, Koncz I. Magyar T, et al. Among authors: gyore b. Can J Physiol Pharmacol. 2021 Feb;99(2):247-253. doi: 10.1139/cjpp-2020-0408. Epub 2020 Nov 26. Can J Physiol Pharmacol. 2021. PMID: 33242286
Cardiac electrophysiological effects of ibuprofen in dog and rabbit ventricular preparations: possible implication to enhanced proarrhythmic risk.
Pászti B, Prorok J, Magyar T, Árpádffy-Lovas T, Györe B, Topál L, Gazdag P, Szlovák J, Naveed M, Jost N, Nagy N, Varró A, Virág L, Koncz I. Pászti B, et al. Among authors: gyore b. Can J Physiol Pharmacol. 2021 Jan;99(1):102-109. doi: 10.1139/cjpp-2020-0386. Epub 2020 Sep 16. Can J Physiol Pharmacol. 2021. PMID: 32937079