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Evaluation of bovine milk extracellular vesicles for the delivery of locked nucleic acid antisense oligonucleotides.
Grossen P, Portmann M, Koller E, Duschmalé M, Minz T, Sewing S, Pandya NJ, van Geijtenbeek SK, Ducret A, Kusznir EA, Huber S, Berrera M, Lauer ME, Ringler P, Nordbo B, Jensen ML, Sladojevich F, Jagasia R, Alex R, Gamboni R, Keller M. Grossen P, et al. Among authors: sewing s. Eur J Pharm Biopharm. 2021 Jan;158:198-210. doi: 10.1016/j.ejpb.2020.11.012. Epub 2020 Nov 26. Eur J Pharm Biopharm. 2021. PMID: 33248268
Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats.
Romero-Palomo F, Festag M, Lenz B, Schadt S, Brink A, Kipar A, Steinhuber B, Husser C, Koller E, Sewing S, Tessier Y, Dzygiel P, Fischer G, Winter M, Hetzel U, Mihatsch MJ, Braendli-Baiocco A. Romero-Palomo F, et al. Among authors: sewing s. Toxicol Pathol. 2021 Aug;49(6):1174-1192. doi: 10.1177/01926233211011615. Epub 2021 Jun 1. Toxicol Pathol. 2021. PMID: 34060347
Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers.
Duschmalé J, Schäublin A, Funder E, Schmidt S, Kiełpiński ŁJ, Nymark H, Jensen K, Koch T, Duschmalé M, Koller E, Møller MR, Schadt S, Husser C, Brink A, Sewing S, Minz T, Wengel J, Bleicher K, Li M. Duschmalé J, et al. Among authors: sewing s. Mol Ther Nucleic Acids. 2022 Jun 22;29:176-188. doi: 10.1016/j.omtn.2022.06.010. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 35860384 Free PMC article.
Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling.
Moisan A, Gubler M, Zhang JD, Tessier Y, Dumong Erichsen K, Sewing S, Gérard R, Avignon B, Huber S, Benmansour F, Chen X, Villaseñor R, Braendli-Baiocco A, Festag M, Maunz A, Singer T, Schuler F, Roth AB. Moisan A, et al. Among authors: sewing s. Mol Ther Nucleic Acids. 2017 Mar 17;6:89-105. doi: 10.1016/j.omtn.2016.11.006. Epub 2016 Dec 10. Mol Ther Nucleic Acids. 2017. PMID: 28325303 Free PMC article.
Combining In Vivo and Organotypic In Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator.
Nudischer R, Renggli K, Bertinetti-Lapatki C, Hoflack JC, Flint N, Sewing S, Pedersen L, Schadt S, Higgins LG, Vardy A, Lenz B, Gand L, Boess F, Elcombe BM, Hierlemann A, Roth AB. Nudischer R, et al. Among authors: sewing s. Toxicol Sci. 2020 Aug 1;176(2):329-342. doi: 10.1093/toxsci/kfaa076. Toxicol Sci. 2020. PMID: 32458970
44 results