Mitchell DA - Search Results

1

Reactivity-Based Screening for Citrulline-Containing Natural Products Reveals a Family of Bacterial Peptidyl Arginine Deiminases.

Harris LA, Saint-Vincent PMB, Guo X, Hudson GA, DiCaprio AJ, Zhu L, Mitchell DA. Harris LA, et al. Among authors: mitchell da. ACS Chem Biol. 2020 Dec 18;15(12):3167-3175. doi: 10.1021/acschembio.0c00685. Epub 2020 Nov 29. ACS Chem Biol. 2020. PMID: 33249828 Free PMC article.

2

Synthesis of plantazolicin analogues enables dissection of ligand binding interactions of a highly selective methyltransferase.

Sharma A, Saint-Vincent PMB, Mitchell DA. Sharma A, et al. Among authors: mitchell da. Org Lett. 2013 Oct 4;15(19):5076-9. doi: 10.1021/ol402444a. Epub 2013 Sep 24. Org Lett. 2013. PMID: 24063702 Free PMC article.

3

Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso Peptide from an understudied halophilic actinomycete.

Metelev M, Tietz JI, Melby JO, Blair PM, Zhu L, Livnat I, Severinov K, Mitchell DA. Metelev M, et al. Among authors: mitchell da. Chem Biol. 2015 Feb 19;22(2):241-50. doi: 10.1016/j.chembiol.2014.11.017. Epub 2015 Jan 15. Chem Biol. 2015. PMID: 25601074 Free PMC article.

4

Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin.

Hao Y, Saint-Vincent PMB, Sharma A, Mitchell DA, Nair SK. Hao Y, et al. Among authors: mitchell da. ACS Chem Biol. 2015 May 15;10(5):1209-1216. doi: 10.1021/cb501042a. Epub 2015 Feb 11. ACS Chem Biol. 2015. PMID: 25635336 Free PMC article.

5

A prevalent peptide-binding domain guides ribosomal natural product biosynthesis.

Burkhart BJ, Hudson GA, Dunbar KL, Mitchell DA. Burkhart BJ, et al. Among authors: mitchell da. Nat Chem Biol. 2015 Aug;11(8):564-70. doi: 10.1038/nchembio.1856. Epub 2015 Jul 13. Nat Chem Biol. 2015. PMID: 26167873 Free PMC article.

6

In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin.

Hudson GA, Zhang Z, Tietz JI, Mitchell DA, van der Donk WA. Hudson GA, et al. Among authors: mitchell da. J Am Chem Soc. 2015 Dec 30;137(51):16012-5. doi: 10.1021/jacs.5b10194. Epub 2015 Dec 21. J Am Chem Soc. 2015. PMID: 26675417 Free PMC article.

7

Plantazolicin is an ultra-narrow spectrum antibiotic that targets the Bacillus anthracis membrane.

Molohon KJ, Saint-Vincent PMB, Park S, Doroghazi JR, Maxson T, Hershfield JR, Flatt KM, Schroeder NE, Ha T, Mitchell DA. Molohon KJ, et al. Among authors: mitchell da. ACS Infect Dis. 2016 Mar 10;2(3):207-220. doi: 10.1021/acsinfecdis.5b00115. Epub 2015 Dec 23. ACS Infect Dis. 2016. PMID: 27152321 Free PMC article.

8

In Vitro Biosynthesis and Substrate Tolerance of the Plantazolicin Family of Natural Products.

Deane CD, Burkhart BJ, Saint-Vincent PMB, Tietz JI, Lin A, Mitchell DA. Deane CD, et al. Among authors: mitchell da. ACS Chem Biol. 2016 Aug 19;11(8):2232-43. doi: 10.1021/acschembio.6b00369. Epub 2016 Jun 16. ACS Chem Biol. 2016. PMID: 27248686 Free PMC article.

9

Biosynthetic Timing and Substrate Specificity for the Thiopeptide Thiomuracin.

Zhang Z, Hudson GA, Mahanta N, Tietz JI, van der Donk WA, Mitchell DA. Zhang Z, et al. Among authors: mitchell da. J Am Chem Soc. 2016 Dec 7;138(48):15511-15514. doi: 10.1021/jacs.6b08987. Epub 2016 Oct 13. J Am Chem Soc. 2016. PMID: 27700071 Free PMC article.

10

Targeting Reactive Carbonyls for Identifying Natural Products and Their Biosynthetic Origins.

Maxson T, Tietz JI, Hudson GA, Guo XR, Tai HC, Mitchell DA. Maxson T, et al. Among authors: mitchell da. J Am Chem Soc. 2016 Nov 23;138(46):15157-15166. doi: 10.1021/jacs.6b06848. Epub 2016 Nov 14. J Am Chem Soc. 2016. PMID: 27797509 Free PMC article.

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