Haavik J - Search Results

1

Structure and substrate specificity determinants of the taurine biosynthetic enzyme cysteine sulphinic acid decarboxylase.

Mahootchi E, Raasakka A, Luan W, Muruganandam G, Loris R, Haavik J, Kursula P. Mahootchi E, et al. Among authors: haavik j. J Struct Biol. 2021 Mar;213(1):107674. doi: 10.1016/j.jsb.2020.107674. Epub 2020 Nov 27. J Struct Biol. 2021. PMID: 33253877 Free article.

2

Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression.

Winge I, Teigen K, Fossbakk A, Mahootchi E, Kleppe R, Sköldberg F, Kämpe O, Haavik J. Winge I, et al. Among authors: haavik j. Neurochem Int. 2015 Nov;90:173-84. doi: 10.1016/j.neuint.2015.08.013. Epub 2015 Sep 1. Neurochem Int. 2015. PMID: 26327310 Free article.

3

Structure of the mouse acidic amino acid decarboxylase GADL1.

Raasakka A, Mahootchi E, Winge I, Luan W, Kursula P, Haavik J. Raasakka A, et al. Among authors: haavik j. Acta Crystallogr F Struct Biol Commun. 2018 Jan 1;74(Pt 1):65-73. doi: 10.1107/S2053230X17017848. Epub 2018 Jan 1. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29372909 Free PMC article.

4

The quaternary structure of human tyrosine hydroxylase: effects of dystonia-associated missense variants on oligomeric state and enzyme activity.

Szigetvari PD, Muruganandam G, Kallio JP, Hallin EI, Fossbakk A, Loris R, Kursula I, Møller LB, Knappskog PM, Kursula P, Haavik J. Szigetvari PD, et al. Among authors: haavik j. J Neurochem. 2019 Jan;148(2):291-306. doi: 10.1111/jnc.14624. Epub 2018 Dec 9. J Neurochem. 2019. PMID: 30411798 Free PMC article.

5

GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production.

Mahootchi E, Cannon Homaei S, Kleppe R, Winge I, Hegvik TA, Megias-Perez R, Totland C, Mogavero F, Baumann A, Glennon JC, Miletic H, Kursula P, Haavik J. Mahootchi E, et al. Among authors: haavik j. Sci Adv. 2020 Jul 17;6(29):eabb3713. doi: 10.1126/sciadv.abb3713. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32733999 Free PMC article.

6

Characterization of a novel pterin intermediate formed in the catalytic cycle of tyrosine hydroxylase.

Almås B, Haavik J, Flatmark T. Almås B, et al. Among authors: haavik j. Biochem J. 1996 Nov 1;319 ( Pt 3)(Pt 3):947-51. doi: 10.1042/bj3190947. Biochem J. 1996. PMID: 8921004 Free PMC article.

7

Inhibition of aromatic L-amino acid decarboxylase activity by human autoantibodies.

Husebye ES, Boe AS, Rorsman F, Kämpe O, Aakvaag A, Rygh T, Flatmark T, Haavik J. Husebye ES, et al. Among authors: haavik j. Clin Exp Immunol. 2000 Jun;120(3):420-3. doi: 10.1046/j.1365-2249.2000.01250.x. Clin Exp Immunol. 2000. PMID: 10844518 Free PMC article.

8

A structural approach into human tryptophan hydroxylase and its implications for the regulation of serotonin biosynthesis.

Martínez A, Knappskog PM, Haavik J. Martínez A, et al. Among authors: haavik j. Curr Med Chem. 2001 Jul;8(9):1077-91. doi: 10.2174/0929867013372616. Curr Med Chem. 2001. PMID: 11472242 Review.

9

Conformation of the substrate and pterin cofactor bound to human tryptophan hydroxylase. Important role of Phe313 in substrate specificity.

McKinney J, Teigen K, Frøystein NA, Salaün C, Knappskog PM, Haavik J, Martínez A. McKinney J, et al. Among authors: haavik j. Biochemistry. 2001 Dec 25;40(51):15591-601. doi: 10.1021/bi015722x. Biochemistry. 2001. PMID: 11747434

10

Tetrahydrobiopterin binding to aromatic amino acid hydroxylases. Ligand recognition and specificity.

Teigen K, Dao KK, McKinney JA, Gorren AC, Mayer B, Frøystein NA, Haavik J, Martínez A. Teigen K, et al. Among authors: haavik j. J Med Chem. 2004 Nov 18;47(24):5962-71. doi: 10.1021/jm0497646. J Med Chem. 2004. PMID: 15537351

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