Wang Y - Search Results

1

First orally bioavailable prodrug of proteolysis targeting chimera (PROTAC) degrades cyclin-dependent kinases 2/4/6 in vivo.

Wei M, Zhao R, Cao Y, Wei Y, Li M, Dong Z, Liu Y, Ruan H, Li Y, Cao S, Tang Z, Zhou Y, Song W, Wang Y, Wang J, Yang G, Yang C. Wei M, et al. Among authors: wang j, wang y. Eur J Med Chem. 2021 Jan 1;209:112903. doi: 10.1016/j.ejmech.2020.112903. Epub 2020 Oct 9. Eur J Med Chem. 2021. PMID: 33256948

2

In vitro and in vivo degradation of programmed cell death ligand 1 (PD-L1) by a proteolysis targeting chimera (PROTAC).

Wang Y, Zhou Y, Cao S, Sun Y, Dong Z, Li C, Wang H, Yao Y, Yu H, Song X, Li M, Wang J, Wei M, Yang G, Yang C. Wang Y, et al. Among authors: wang h, wang j. Bioorg Chem. 2021 Jun;111:104833. doi: 10.1016/j.bioorg.2021.104833. Epub 2021 Mar 19. Bioorg Chem. 2021. PMID: 33839580

3

Discovery and Optimization of a Novel 2H-Pyrazolo[3,4-d]pyrimidine Derivative as a Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitor.

Wei Y, Tang Y, Zhou Y, Yang Y, Cui Y, Wang X, Wang Y, Liu Y, Liu N, Wang Q, Li C, Ruan H, Zhou H, Wei M, Yang G, Yang C. Wei Y, et al. Among authors: wang x, wang y, wang q. J Med Chem. 2021 Jul 8;64(13):9078-9099. doi: 10.1021/acs.jmedchem.1c00174. Epub 2021 Jun 15. J Med Chem. 2021. PMID: 34129329

4

Design and discovery of new selective and potent VEGF receptor 2 tyrosine kinase inhibitors.

Hou F, Yao Y, Wei Y, Wang Y, Cao Y, Liu X, Zheng L, Zhang Q, Jiao Y, Chen Y, Meng Y, Sun Y, Wu Y, Wang J, Wang J, Wu Z, Zhang K, Wei M, Yang G. Hou F, et al. Among authors: wang j, wang y. Bioorg Med Chem. 2023 Aug 15;91:117404. doi: 10.1016/j.bmc.2023.117404. Epub 2023 Jul 3. Bioorg Med Chem. 2023. PMID: 37429211

5

Discovery of Selective and Potent ATR Degrader for Exploration its Kinase-Independent Functions in Acute Myeloid Leukemia Cells.

Wang Y, Wang R, Zhao Y, Cao S, Li C, Wu Y, Ma L, Liu Y, Yao Y, Jiao Y, Chen Y, Liu S, Zhang K, Wei M, Yang C, Yang G. Wang Y, et al. Among authors: wang r. Angew Chem Int Ed Engl. 2024 Apr 22;63(17):e202318568. doi: 10.1002/anie.202318568. Epub 2024 Mar 21. Angew Chem Int Ed Engl. 2024. PMID: 38433368

6

Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor.

Wang Y, Liu Y, Zhang Y, Zhang Z, Xu L, Wang J, Yang Y, Hu B, Yao Y, Wei M, Wang J, Tang B, Zhang K, Liu S, Yang G. Wang Y, et al. Among authors: wang j. Eur J Med Chem. 2024 May 5;271:116395. doi: 10.1016/j.ejmech.2024.116395. Epub 2024 Apr 12. Eur J Med Chem. 2024. PMID: 38626523

7

The synthesis and effects of a novel TRPC6 inhibitor, BP3112, on hepatocellular carcinoma.

Qiao R, Fan X, Zhou L, Dong D, Liu Y, Liu D, Ma G, Tang N, Wang Y, Li XQ, Ren L, Cao W. Qiao R, et al. Among authors: wang y. Future Med Chem. 2023 Apr;15(7):629-646. doi: 10.4155/fmc-2022-0313. Epub 2023 May 3. Future Med Chem. 2023. PMID: 37132400

8

Production of high affinity monoclonal antibody and development of indirect competitive chemiluminescence enzyme immunoassay for gentamicin residue in animal tissues.

Dai P, Zhang Y, Hong Y, Xiong J, Du H, Duan L, Wang D, Wang Y, Deng W, Hammock BD, Yang W. Dai P, et al. Among authors: wang y, wang d. Food Chem. 2023 Jan 30;400:134067. doi: 10.1016/j.foodchem.2022.134067. Epub 2022 Sep 5. Food Chem. 2023. PMID: 36084594

9

Comparison of results among UBE-TLIF, MIS-TLIF and open TLIF for Meyerding grade I lumbar spondylolisthesis: a retrospective study.

Lu Z, Zhong D, Liu Y, Zhao G, Ke Z, Wang Y. Lu Z, et al. Among authors: wang y. BMC Surg. 2024 Nov 13;24(1):355. doi: 10.1186/s12893-024-02651-5. BMC Surg. 2024. PMID: 39538275

10

Adipokines and their potential impacts on susceptibility to myocardial ischemia/reperfusion injury in diabetes.

Han R, Huang H, Zhu J, Jin X, Wang Y, Xu Y, Xia Z. Han R, et al. Among authors: wang y. Lipids Health Dis. 2024 Nov 13;23(1):372. doi: 10.1186/s12944-024-02357-w. Lipids Health Dis. 2024. PMID: 39538244 Review.

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