Yang G - Search Results

1

First orally bioavailable prodrug of proteolysis targeting chimera (PROTAC) degrades cyclin-dependent kinases 2/4/6 in vivo.

Wei M, Zhao R, Cao Y, Wei Y, Li M, Dong Z, Liu Y, Ruan H, Li Y, Cao S, Tang Z, Zhou Y, Song W, Wang Y, Wang J, Yang G, Yang C. Wei M, et al. Among authors: yang c, yang g. Eur J Med Chem. 2021 Jan 1;209:112903. doi: 10.1016/j.ejmech.2020.112903. Epub 2020 Oct 9. Eur J Med Chem. 2021. PMID: 33256948

2

Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids.

Liu X, Li B, Zhang Z, Wei Y, Xu Z, Qin S, Liu N, Zhao R, Peng J, Yang G, Qi M, Liu T, Xie M, Liu S, Gao X, Lu C, Zhu L, Long X, Kang H, Sun T, Zhou H, Wei M, Yang G, Yang C. Liu X, et al. Among authors: yang c, yang g. J Med Chem. 2018 Dec 13;61(23):10814-10833. doi: 10.1021/acs.jmedchem.8b01445. Epub 2018 Nov 29. J Med Chem. 2018. PMID: 30433783

3

Design and synthesis of novel Flavone-based histone deacetylase inhibitors antagonizing activation of STAT3 in breast cancer.

Wei M, Xie M, Zhang Z, Wei Y, Zhang J, Pan H, Li B, Wang J, Song Y, Chong C, Zhao R, Wang J, Yu L, Yang G, Yang C. Wei M, et al. Among authors: yang c, yang g. Eur J Med Chem. 2020 Nov 15;206:112677. doi: 10.1016/j.ejmech.2020.112677. Epub 2020 Aug 1. Eur J Med Chem. 2020. PMID: 32823005

4

In vitro and in vivo degradation of programmed cell death ligand 1 (PD-L1) by a proteolysis targeting chimera (PROTAC).

Wang Y, Zhou Y, Cao S, Sun Y, Dong Z, Li C, Wang H, Yao Y, Yu H, Song X, Li M, Wang J, Wei M, Yang G, Yang C. Wang Y, et al. Among authors: yang c, yang g. Bioorg Chem. 2021 Jun;111:104833. doi: 10.1016/j.bioorg.2021.104833. Epub 2021 Mar 19. Bioorg Chem. 2021. PMID: 33839580

5

Discovery of a novel Pleuromutilin derivative as anti-IPF lead compound via high-throughput assay.

Zhang K, Liang J, Wang N, Li N, Jiang Y, Li X, Yang C, Zhou H, Yang G. Zhang K, et al. Among authors: yang c, yang g. Eur J Med Chem. 2022 Nov 5;241:114643. doi: 10.1016/j.ejmech.2022.114643. Epub 2022 Aug 6. Eur J Med Chem. 2022. PMID: 35961069

6

Design and synthesis of Leukotriene A4 hydrolase inhibitors to alleviate idiopathic pulmonary fibrosis and acute lung injury.

Li X, Xie M, Lu C, Mao J, Cao Y, Yang Y, Wei Y, Liu X, Cao S, Song Y, Peng J, Zhou Y, Jiang Q, Lin G, Qin S, Qi M, Hou M, Liu X, Zhou H, Yang G, Yang C. Li X, et al. Among authors: yang c, yang g, yang y. Eur J Med Chem. 2020 Oct 1;203:112614. doi: 10.1016/j.ejmech.2020.112614. Epub 2020 Jul 11. Eur J Med Chem. 2020. PMID: 32679453

7

Corrigendum to 'Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-b1 pathway' [Eur. J. Med. Chem. 157 (2018) 229-247].

Li X, Lu C, Liu S, Liu S, Su C, Xiao T, Bi Z, Sheng P, Huang M, Liu X, Wei Y, Zhao L, Miao S, Mao J, Huang K, Gao S, Liu N, Qi M, Liu T, Qin S, Wei L, Sun T, Ning W, Yang G, Zhou H, Yang C. Li X, et al. Among authors: yang c, yang g. Eur J Med Chem. 2019 Feb 1;163:403. doi: 10.1016/j.ejmech.2018.11.071. Epub 2018 Dec 7. Eur J Med Chem. 2019. PMID: 30530191 No abstract available.

8

A novel epigenetic drug conjugating flavonoid and HDAC inhibitor confer suppression of acute myeloid leukemogenesis.

Zhang J, Gao X, Wei M, Li Y, Yang G, Yang C, Yu L. Zhang J, et al. Among authors: yang c, yang g. Clin Sci (Lond). 2021 Jul 30;135(14):1751-1765. doi: 10.1042/CS20210571. Clin Sci (Lond). 2021. PMID: 34282832

9

Deglycosylated Azithromycin Targets Transgelin to Enhance Intestinal Smooth Muscle Function.

Zhong W, Sun B, Ruan H, Yang G, Qian B, Cao H, He L, Fan Y, Roberts AG, Liu X, Hu X, Liang Y, Ye Q, Yin T, Wang B, Yang C, Sun T, Zhou H. Zhong W, et al. Among authors: yang c, yang g. iScience. 2020 Aug 14;23(9):101464. doi: 10.1016/j.isci.2020.101464. eCollection 2020 Sep 25. iScience. 2020. PMID: 32889431 Free PMC article.

10

Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway.

Li X, Huang K, Liu X, Ruan H, Ma L, Liang J, Cui Y, Wang Y, Wu S, Li H, Wei Y, Li Z, Gao J, Yang B, Li X, Yang G, Zhou H, Yang C. Li X, et al. Among authors: yang c, yang b, yang g. Front Pharmacol. 2021 Apr 12;12:639574. doi: 10.3389/fphar.2021.639574. eCollection 2021. Front Pharmacol. 2021. PMID: 33912053 Free PMC article.

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