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889 results

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Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.
Tengesdal IW, Menon DR, Osborne DG, Neff CP, Powers NE, Gamboni F, Mauro AG, D'Alessandro A, Stefanoni D, Henen MA, Mills TS, De Graaf DM, Azam T, Vogeli B, Palmer BE, Pietras EM, DeGregori J, Tan AC, Joosten LAB, Fujita M, Dinarello CA, Marchetti C. Tengesdal IW, et al. Among authors: marchetti c. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2000915118. doi: 10.1073/pnas.2000915118. Proc Natl Acad Sci U S A. 2021. PMID: 33649199 Free PMC article.
Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.
Amo-Aparicio J, Dominguez A, Atif SM, Dinarello A, Azam T, Alula KM, Piper M, Lieu CH, Lentz RW, Leal AD, Bagby SM, Messersmith WA, Karam SD, Dinarello CA, Pitts TM, Marchetti C. Amo-Aparicio J, et al. Among authors: marchetti c. Cancer Res Commun. 2023 Sep 20;3(9):1899-1911. doi: 10.1158/2767-9764.CRC-23-0065. Cancer Res Commun. 2023. PMID: 37772994 Free PMC article.
NLRP3 and cancer: Pathogenesis and therapeutic opportunities.
Tengesdal IW, Dinarello CA, Marchetti C. Tengesdal IW, et al. Among authors: marchetti c. Pharmacol Ther. 2023 Nov;251:108545. doi: 10.1016/j.pharmthera.2023.108545. Epub 2023 Oct 21. Pharmacol Ther. 2023. PMID: 37866732 Free PMC article. Review.
IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1β secretion.
Dinarello A, May M, Amo-Aparicio J, Azam T, Gaballa JM, Marchetti C, Tesoriere A, Ghirardo R, Redzic JS, Webber WS 3rd, Atif SM, Li S, Eisenmesser EZ, de Graaf DM, Dinarello CA. Dinarello A, et al. Among authors: marchetti c. Proc Natl Acad Sci U S A. 2023 Nov 7;120(45):e2306476120. doi: 10.1073/pnas.2306476120. Epub 2023 Oct 31. Proc Natl Acad Sci U S A. 2023. PMID: 37906644 Free PMC article.
International nomenclature guidelines for the IL-1 family of cytokines and receptors.
Gaballa JM, Højen JF, De Graaf DM, Amo-Aparicio J, Marchetti C, Cavalli G, Dinarello A, Li S, Corbisiero MF, Tengesdal IW, Redzic JS, Azam T, Webber WS 3rd, Pankratz KA, May MJ, Cominelli F, Eisenmesser EZ, Kim S, Dinarello CA, Boraschi D. Gaballa JM, et al. Among authors: marchetti c. Nat Immunol. 2024 Apr;25(4):581-582. doi: 10.1038/s41590-024-01777-1. Nat Immunol. 2024. PMID: 38499798 No abstract available.
Inflammation promotes aging-associated oncogenesis in the lung.
Pham-Danis C, Chia SB, Scarborough HA, Danis E, Nemkov T, Kleczko EK, Navarro A, Goodspeed A, Bonney EA, Dinarello CA, Marchetti C, Nemenoff RA, Hansen K, DeGregori J. Pham-Danis C, et al. Among authors: marchetti c. bioRxiv [Preprint]. 2024 Mar 5:2024.03.01.583044. doi: 10.1101/2024.03.01.583044. bioRxiv. 2024. PMID: 38496448 Free PMC article. Preprint.
Actionable mutations in early-stage ovarian cancer according to the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT): a descriptive analysis on a large prospective cohort.
Camarda F, Mastrantoni L, Parrillo C, Minucci A, Persiani F, Giannarelli D, Pasciuto T, Giacomini F, De Paolis E, Manfredelli M, Marchetti C, Zannoni GF, Fagotti A, Scambia G, Nero C. Camarda F, et al. Among authors: marchetti c. ESMO Open. 2024 Dec 19;10(1):104090. doi: 10.1016/j.esmoop.2024.104090. Online ahead of print. ESMO Open. 2024. PMID: 39705839 Free article.
889 results