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A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling.
Grimsey NJ, Narala R, Rada CC, Mehta S, Stephens BS, Kufareva I, Lapek J, Gonzalez DJ, Handel TM, Zhang J, Trejo J. Grimsey NJ, et al. Among authors: trejo j. Cell Rep. 2018 Sep 18;24(12):3312-3323.e5. doi: 10.1016/j.celrep.2018.08.061. Cell Rep. 2018. PMID: 30232011 Free PMC article.
Subcellular hot spots of GPCR signaling promote vascular inflammation.
Birch CA, Molinar-Inglis O, Trejo J. Birch CA, et al. Among authors: trejo j. Curr Opin Endocr Metab Res. 2021 Feb;16:37-42. doi: 10.1016/j.coemr.2020.07.011. Epub 2020 Aug 18. Curr Opin Endocr Metab Res. 2021. PMID: 32838054 Free PMC article. Review.
aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis.
Molinar-Inglis O, Birch CA, Nicholas D, Orduña-Castillo L, Cisneros-Aguirre M, Patwardhan A, Chen B, Grimsey NJ, Coronel LJ, Lin H, Gomez Menzies PK, Lawson MA, Patel HH, Trejo J. Molinar-Inglis O, et al. Among authors: trejo j. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2106623118. doi: 10.1073/pnas.2106623118. Proc Natl Acad Sci U S A. 2021. PMID: 34873055 Free PMC article.
248 results