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132 results

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Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial.
Cortes J, Cescon DW, Rugo HS, Nowecki Z, Im SA, Yusof MM, Gallardo C, Lipatov O, Barrios CH, Holgado E, Iwata H, Masuda N, Otero MT, Gokmen E, Loi S, Guo Z, Zhao J, Aktan G, Karantza V, Schmid P; KEYNOTE-355 Investigators. Cortes J, et al. Among authors: cescon dw. Lancet. 2020 Dec 5;396(10265):1817-1828. doi: 10.1016/S0140-6736(20)32531-9. Lancet. 2020. PMID: 33278935 Clinical Trial.
The Clinical, Genomic, and Transcriptomic Landscape of BRAF Mutant Cancers.
Kazandjian S, Rousselle E, Dankner M, Cescon DW, Spreafico A, Ma K, Kavan P, Batist G, Rose AAN. Kazandjian S, et al. Among authors: cescon dw. Cancers (Basel). 2024 Jan 19;16(2):445. doi: 10.3390/cancers16020445. Cancers (Basel). 2024. PMID: 38275886 Free PMC article.
Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification.
Zhang C, Wu BZ, Di Ciano-Oliveira C, Wu YF, Khavkine Binstock SS, Soria-Bretones I, Pham NA, Elia AJ, Chari R, Lam WL, Bray MR, Mak TW, Tsao MS, Cescon DW, Thu KL. Zhang C, et al. Among authors: cescon dw. Cancer Gene Ther. 2024 Oct;31(10):1559-1570. doi: 10.1038/s41417-024-00824-1. Epub 2024 Aug 24. Cancer Gene Ther. 2024. PMID: 39179685 Free PMC article.
Pembrolizumab monotherapy for previously untreated, PD-L1-positive, metastatic triple-negative breast cancer: cohort B of the phase II KEYNOTE-086 study.
Adams S, Loi S, Toppmeyer D, Cescon DW, De Laurentiis M, Nanda R, Winer EP, Mukai H, Tamura K, Armstrong A, Liu MC, Iwata H, Ryvo L, Wimberger P, Rugo HS, Tan AR, Jia L, Ding Y, Karantza V, Schmid P. Adams S, et al. Among authors: cescon dw. Ann Oncol. 2019 Mar 1;30(3):405-411. doi: 10.1093/annonc/mdy518. Ann Oncol. 2019. PMID: 30475947 Free article. Clinical Trial.
Pembrolizumab monotherapy for previously treated metastatic triple-negative breast cancer: cohort A of the phase II KEYNOTE-086 study.
Adams S, Schmid P, Rugo HS, Winer EP, Loirat D, Awada A, Cescon DW, Iwata H, Campone M, Nanda R, Hui R, Curigliano G, Toppmeyer D, O'Shaughnessy J, Loi S, Paluch-Shimon S, Tan AR, Card D, Zhao J, Karantza V, Cortés J. Adams S, et al. Among authors: cescon dw. Ann Oncol. 2019 Mar 1;30(3):397-404. doi: 10.1093/annonc/mdy517. Ann Oncol. 2019. PMID: 30475950 Free article. Clinical Trial.
Patterns of Recurrence and Predictors of Survival in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy, Surgery, and Radiation.
Keilty D, Nezafat Namini S, Swain M, Maganti M, Cil TD, McCready DR, Cescon DW, Amir E, Fleming R, Mulligan AM, Fyles A, Croke JM, Liu FF, Levin W, Koch CA, Han K. Keilty D, et al. Among authors: cescon dw. Int J Radiat Oncol Biol Phys. 2020 Nov 1;108(3):676-685. doi: 10.1016/j.ijrobp.2020.04.044. Epub 2020 May 11. Int J Radiat Oncol Biol Phys. 2020. PMID: 32407932
Transcriptomic Determinants of Response to Pembrolizumab Monotherapy across Solid Tumor Types.
Cristescu R, Nebozhyn M, Zhang C, Albright A, Kobie J, Huang L, Zhao Q, Wang A, Ma H, Alexander Cao Z, Morrissey M, Ribas A, Grivas P, Cescon DW, McClanahan TK, Snyder A, Ayers M, Lunceford J, Loboda A. Cristescu R, et al. Among authors: cescon dw. Clin Cancer Res. 2022 Apr 14;28(8):1680-1689. doi: 10.1158/1078-0432.CCR-21-3329. Clin Cancer Res. 2022. PMID: 34965943 Free PMC article.
132 results