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A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.
Macdonald WA, Purcell AW, Mifsud NA, Ely LK, Williams DS, Chang L, Gorman JJ, Clements CS, Kjer-Nielsen L, Koelle DM, Burrows SR, Tait BD, Holdsworth R, Brooks AG, Lovrecz GO, Lu L, Rossjohn J, McCluskey J. Macdonald WA, et al. Among authors: purcell aw. J Exp Med. 2003 Sep 1;198(5):679-91. doi: 10.1084/jem.20030066. Epub 2003 Aug 25. J Exp Med. 2003. PMID: 12939341 Free PMC article.
Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion.
Zernich D, Purcell AW, Macdonald WA, Kjer-Nielsen L, Ely LK, Laham N, Crockford T, Mifsud NA, Bharadwaj M, Chang L, Tait BD, Holdsworth R, Brooks AG, Bottomley SP, Beddoe T, Peh CA, Rossjohn J, McCluskey J. Zernich D, et al. Among authors: purcell aw. J Exp Med. 2004 Jul 5;200(1):13-24. doi: 10.1084/jem.20031680. Epub 2004 Jun 28. J Exp Med. 2004. PMID: 15226359 Free PMC article.
Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes.
Petersen J, Wurzbacher SJ, Williamson NA, Ramarathinam SH, Reid HH, Nair AK, Zhao AY, Nastovska R, Rudge G, Rossjohn J, Purcell AW. Petersen J, et al. Among authors: purcell aw. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2776-81. doi: 10.1073/pnas.0812901106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196958 Free PMC article.
328 results