van den Biggelaar M - Search Results

1

Hydrogen-Deuterium Exchange Mass Spectrometry Identifies Activated Factor IX-Induced molecular Changes in Activated Factor VIII.

van Galen J, Freato N, Przeradzka MA, Ebberink EHTM, Boon-Spijker M, van der Zwaan C, van den Biggelaar M, Meijer AB. van Galen J, et al. Among authors: van der zwaan c, van den biggelaar m. Thromb Haemost. 2021 May;121(5):594-602. doi: 10.1055/s-0040-1721422. Epub 2020 Dec 10. Thromb Haemost. 2021. PMID: 33302303

2

Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies.

van den Biggelaar M, Bierings R, Storm G, Voorberg J, Mertens K. van den Biggelaar M, et al. J Thromb Haemost. 2007 Nov;5(11):2235-42. doi: 10.1111/j.1538-7836.2007.02737.x. J Thromb Haemost. 2007. PMID: 17958741 Free article.

3

Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles.

van den Biggelaar M, Meijer AB, Voorberg J, Mertens K. van den Biggelaar M, et al. Blood. 2009 Mar 26;113(13):3102-9. doi: 10.1182/blood-2008-05-159699. Epub 2008 Dec 16. Blood. 2009. PMID: 19088379 Free article.

4

A single lysine of the two-lysine recognition motif of the D3 domain of receptor-associated protein is sufficient to mediate endocytosis by low-density lipoprotein receptor-related protein.

van den Biggelaar M, Sellink E, Klein Gebbinck JW, Mertens K, Meijer AB. van den Biggelaar M, et al. Int J Biochem Cell Biol. 2011 Mar;43(3):431-40. doi: 10.1016/j.biocel.2010.11.017. Epub 2010 Dec 7. Int J Biochem Cell Biol. 2011. PMID: 21144910

5

C1 domain residues Lys 2092 and Phe 2093 are of major importance for the endocytic uptake of coagulation factor VIII.

Meems H, van den Biggelaar M, Rondaij M, van der Zwaan C, Mertens K, Meijer AB. Meems H, et al. Among authors: van der zwaan c, van den biggelaar m. Int J Biochem Cell Biol. 2011 Aug;43(8):1114-21. doi: 10.1016/j.biocel.2011.03.014. Epub 2011 Apr 8. Int J Biochem Cell Biol. 2011. PMID: 21497669

6

Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain.

Herczenik E, van Haren SD, Wroblewska A, Kaijen P, van den Biggelaar M, Meijer AB, Martinez-Pomares L, ten Brinke A, Voorberg J. Herczenik E, et al. Among authors: van den biggelaar m, van haren sd. J Allergy Clin Immunol. 2012 Feb;129(2):501-9, 509.e1-5. doi: 10.1016/j.jaci.2011.08.029. Epub 2011 Oct 1. J Allergy Clin Immunol. 2012. PMID: 21962992

7

Mass spectrometry-assisted study reveals that lysine residues 1967 and 1968 have opposite contribution to stability of activated factor VIII.

Bloem E, Meems H, van den Biggelaar M, van der Zwaan C, Mertens K, Meijer AB. Bloem E, et al. Among authors: van der zwaan c, van den biggelaar m. J Biol Chem. 2012 Feb 17;287(8):5775-83. doi: 10.1074/jbc.M111.308627. Epub 2012 Jan 3. J Biol Chem. 2012. PMID: 22215677 Free PMC article.

8

Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice.

Wroblewska A, van Haren SD, Herczenik E, Kaijen P, Ruminska A, Jin SY, Zheng XL, van den Biggelaar M, ten Brinke A, Meijer AB, Voorberg J. Wroblewska A, et al. Among authors: van den biggelaar m, van haren sd. Blood. 2012 May 31;119(22):5294-300. doi: 10.1182/blood-2011-11-391680. Epub 2012 Apr 12. Blood. 2012. PMID: 22498747 Free PMC article.

9

Distinct roles of Ser-764 and Lys-773 at the N terminus of von Willebrand factor in complex assembly with coagulation factor VIII.

Castro-Núñez L, Bloem E, Boon-Spijker MG, van der Zwaan C, van den Biggelaar M, Mertens K, Meijer AB. Castro-Núñez L, et al. Among authors: van der zwaan c, van den biggelaar m. J Biol Chem. 2013 Jan 4;288(1):393-400. doi: 10.1074/jbc.M112.400572. Epub 2012 Nov 20. J Biol Chem. 2013. PMID: 23168412 Free PMC article.

10

A3 domain region 1803-1818 contributes to the stability of activated factor VIII and includes a binding site for activated factor IX.

Bloem E, Meems H, van den Biggelaar M, Mertens K, Meijer AB. Bloem E, et al. Among authors: van den biggelaar m. J Biol Chem. 2013 Sep 6;288(36):26105-26111. doi: 10.1074/jbc.M113.500884. Epub 2013 Jul 24. J Biol Chem. 2013. PMID: 23884417 Free PMC article.

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