Manera C - Search Results

1

Positive Allosteric Modulation of CB1 and CB2 Cannabinoid Receptors Enhances the Neuroprotective Activity of a Dual CB1R/CB2R Orthosteric Agonist.

Polini B, Cervetto C, Carpi S, Pelassa S, Gado F, Ferrisi R, Bertini S, Nieri P, Marcoli M, Manera C. Polini B, et al. Among authors: manera c. Life (Basel). 2020 Dec 8;10(12):333. doi: 10.3390/life10120333. Life (Basel). 2020. PMID: 33302569 Free PMC article.

2

Conformationally restrained analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2',5'-morpholines].

Balsamo A, Lapucci A, Manera C, Martinelli A, Nencetti S, Orlandini E, Calderone V, Giannaccini G, Nieri P. Balsamo A, et al. Among authors: manera c. Eur J Med Chem. 2002 Jan;37(1):11-22. doi: 10.1016/s0223-5234(01)01322-8. Eur J Med Chem. 2002. PMID: 11841871

3

4-[6-(Dansylamino)hexylamino]-7-methyl-2-phenyl-1,8-naphthyridine as a new potential fluorescent probe for studying A1-adenosine receptor.

Macchia M, Bertini S, Di Bussolo V, Manera C, Martini C, Minutolo F, Mori C, Saccomanni G, Tuscano D, Ferrarini PL. Macchia M, et al. Among authors: manera c. Farmaco. 2002 Oct;57(10):783-6. doi: 10.1016/s0014-827x(02)01275-2. Farmaco. 2002. PMID: 12420873

4

Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists.

Manera C, Saccomanni G, Adinolfi B, Benetti V, Ligresti A, Cascio MG, Tuccinardi T, Lucchesi V, Martinelli A, Nieri P, Masini E, Di Marzo V, Ferrarini PL. Manera C, et al. J Med Chem. 2009 Jun 25;52(12):3644-51. doi: 10.1021/jm801563d. J Med Chem. 2009. PMID: 19435366

5

Carbazole-containing arylcarboxamides as BACE1 inhibitors.

Bertini S, Asso V, Ghilardi E, Granchi C, Manera C, Minutolo F, Saccomanni G, Bortolato A, Mason J, Moro S, Macchia M. Bertini S, et al. Among authors: manera c. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6657-61. doi: 10.1016/j.bmcl.2011.09.064. Epub 2011 Sep 21. Bioorg Med Chem Lett. 2011. PMID: 21986588

6

Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold.

Manera C, Saccomanni G, Malfitano AM, Bertini S, Castelli F, Laezza C, Ligresti A, Lucchesi V, Tuccinardi T, Rizzolio F, Bifulco M, Di Marzo V, Giordano A, Macchia M, Martinelli A. Manera C, et al. Eur J Med Chem. 2012 Jun;52:284-94. doi: 10.1016/j.ejmech.2012.03.031. Epub 2012 Mar 24. Eur J Med Chem. 2012. PMID: 22483967

7

1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor.

Lucchesi V, Parkkari T, Savinainen JR, Malfitano AM, Allarà M, Bertini S, Castelli F, Del Carlo S, Laezza C, Ligresti A, Saccomanni G, Bifulco M, Di Marzo V, Macchia M, Manera C. Lucchesi V, et al. Among authors: manera c. Eur J Med Chem. 2014 Mar 3;74:524-32. doi: 10.1016/j.ejmech.2013.10.070. Epub 2014 Jan 21. Eur J Med Chem. 2014. PMID: 24518874

8

CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides.

Lucchesi V, Hurst DP, Shore DM, Bertini S, Ehrmann BM, Allarà M, Lawrence L, Ligresti A, Minutolo F, Saccomanni G, Sharir H, Macchia M, Di Marzo V, Abood ME, Reggio PH, Manera C. Lucchesi V, et al. Among authors: manera c. J Med Chem. 2014 Nov 13;57(21):8777-91. doi: 10.1021/jm500807e. Epub 2014 Oct 15. J Med Chem. 2014. PMID: 25272206 Free PMC article.

9

Synthesis, in vitro and in vivo evaluation of 1,3,5-triazines as cannabinoid CB2 receptor agonists.

Yrjölä S, Sarparanta M, Airaksinen AJ, Hytti M, Kauppinen A, Pasonen-Seppänen S, Adinolfi B, Nieri P, Manera C, Keinänen O, Poso A, Nevalainen TJ, Parkkari T. Yrjölä S, et al. Among authors: manera c. Eur J Pharm Sci. 2015 Jan 25;67:85-96. doi: 10.1016/j.ejps.2014.11.003. Epub 2014 Nov 14. Eur J Pharm Sci. 2015. PMID: 25447744

10

Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands.

Bertini S, Parkkari T, Savinainen JR, Arena C, Saccomanni G, Saguto S, Ligresti A, Allarà M, Bruno A, Marinelli L, Di Marzo V, Novellino E, Manera C, Macchia M. Bertini S, et al. Among authors: manera c. Eur J Med Chem. 2015 Jan 27;90:526-36. doi: 10.1016/j.ejmech.2014.11.066. Epub 2014 Dec 2. Eur J Med Chem. 2015. PMID: 25486424

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