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Toward a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part I: which parameters from human studies are most relevant for toxicological assessments?
Sauer UG, Asiimwe A, Botham PA, Charlton A, Hallmark N, Jacobi S, Marty S, Melching-Kollmuss S, Palha JA, Strauss V, van Ravenzwaay B, Swaen G. Sauer UG, et al. Crit Rev Toxicol. 2020 Oct;50(9):740-763. doi: 10.1080/10408444.2020.1839380. Epub 2020 Dec 11. Crit Rev Toxicol. 2020. PMID: 33305658 Review.
Anti-androgenicity can only be evaluated using a weight of evidence approach.
Melching-Kollmuß S, Fussell KC, Buesen R, Dammann M, Schneider S, Tennekes H, van Ravenzwaay B. Melching-Kollmuß S, et al. Regul Toxicol Pharmacol. 2014 Feb;68(1):175-92. doi: 10.1016/j.yrtph.2013.10.004. Epub 2013 Oct 31. Regul Toxicol Pharmacol. 2014. PMID: 24184466 Review.
Adversity Considerations for Thyroid Follicular Cell Hypertrophy and Hyperplasia in Nonclinical Toxicity Studies: Results From the 6th ESTP International Expert Workshop.
Huisinga M, Bertrand L, Chamanza R, Damiani I, Engelhardt J, Francke S, Freyberger A, Harada T, Harleman J, Kaufmann W, Keane K, Köhrle J, Lenz B, Marty MS, Melching-Kollmuss S, Palazzi X, Pohlmeyer-Esch G, Popp A, Rosol TJ, Strauss V, Van den Brink-Knol H, Wood CE, Yoshida M. Huisinga M, et al. Among authors: melching kollmuss s. Toxicol Pathol. 2020 Dec;48(8):920-938. doi: 10.1177/0192623320972009. Toxicol Pathol. 2020. PMID: 33334259
26 results