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Page 1
Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators.
Tomati V, Capurro V, Pesce E, Pastorino C, Sondo E, Lena M, Borrelli A, Cresta F, Pantano S, Collini F, Ripani P, Terlizzi V, Fevola C, Costa S, Lucanto MC, Zara F, Bandiera T, Bocciardi R, Castellani C, Galietta LJV, Pedemonte N. Tomati V, et al. Among authors: capurro v. Front Pharmacol. 2024 Nov 18;15:1494327. doi: 10.3389/fphar.2024.1494327. eCollection 2024. Front Pharmacol. 2024. PMID: 39624835 Free PMC article.
Distinct Responses of Cystic Fibrosis Epithelial Cells to SARS-CoV-2 and Influenza A Virus.
Pagani I, Venturini A, Capurro V, Nonis A, Ghezzi S, Lena M, Alcalá-Franco B, Gianferro F, Guidone D, Colombo C, Pedemonte N, Bragonzi A, Cigana C, Galietta LJV, Vicenzi E. Pagani I, et al. Among authors: capurro v. Am J Respir Cell Mol Biol. 2024 Sep 23. doi: 10.1165/rcmb.2024-0213OC. Online ahead of print. Am J Respir Cell Mol Biol. 2024. PMID: 39311876
Investigation of CFTR Function in Human Nasal Epithelial Cells Informs Personalized Medicine.
Pion A, Kavanagh E, Joynt AT, Raraigh KS, Vanscoy L, Langfelder-Schwind E, McNamara J, Moore B, Patel S, Merlo K, Temme R, Capurro V, Pesce E, Merlo C, Pedemonte N, Cutting GR, Sharma N. Pion A, et al. Among authors: capurro v. Am J Respir Cell Mol Biol. 2024 Nov;71(5):577-588. doi: 10.1165/rcmb.2023-0398OC. Am J Respir Cell Mol Biol. 2024. PMID: 39012815
Tezacaftor is a direct inhibitor of sphingolipid delta-4 desaturase enzyme (DEGS).
Ciobanu DZ, Liessi N, Tomati V, Capurro V, Bertozzi SM, Summa M, Bertorelli R, Loberto N, Dobi D, Aureli M, Nobbio L, Bandiera T, Pedemonte N, Bassi R, Armirotti A. Ciobanu DZ, et al. Among authors: capurro v. J Cyst Fibros. 2024 Nov;23(6):1167-1172. doi: 10.1016/j.jcf.2024.05.004. Epub 2024 May 24. J Cyst Fibros. 2024. PMID: 38789319 Free article.
Rescue by elexacaftor-tezacaftor-ivacaftor of the G1244E cystic fibrosis mutation's stability and gating defects are dependent on cell background.
Tomati V, Costa S, Capurro V, Pesce E, Pastorino C, Lena M, Sondo E, Di Duca M, Cresta F, Cristadoro S, Zara F, Galietta LJV, Bocciardi R, Castellani C, Lucanto MC, Pedemonte N. Tomati V, et al. Among authors: capurro v. J Cyst Fibros. 2023 May;22(3):525-537. doi: 10.1016/j.jcf.2022.12.005. Epub 2022 Dec 19. J Cyst Fibros. 2023. PMID: 36543707
Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19.
Asselta R, Paraboschi EM, Stravalaci M, Invernizzi P, Bonfanti P, Biondi A, Pagani I, Pedotti M, Doni A, Scavello F, Mapelli SN, Sironi M, Perucchini C, Varani L, Matkovic M, Cavalli A, Cesana D, Gallina P, Pedemonte N, Capurro V, Clementi N, Mancini N, Bayarri-Olmos R, Garred P, Rappuoli R, Duga S, Bottazzi B, Uguccioni M, Vicenzi E, Mantovani A, Garlanda C. Asselta R, et al. Among authors: capurro v. Nat Immunol. 2022 Jun;23(6):865-867. doi: 10.1038/s41590-022-01228-9. Epub 2022 May 27. Nat Immunol. 2022. PMID: 35624207 No abstract available.
45 results