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Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep.
Nelvagal HR, Eaton SL, Wang SH, Eultgen EM, Takahashi K, Le SQ, Nesbitt R, Dearborn JT, Siano N, Puhl AC, Dickson PI, Thompson G, Murdoch F, Brennan PM, Gray M, Greenhalgh SN, Tennant P, Gregson R, Clutton E, Nixon J, Proudfoot C, Guido S, Lillico SG, Whitelaw CBA, Lu JY, Hofmann SL, Ekins S, Sands MS, Wishart TM, Cooper JD. Nelvagal HR, et al. Among authors: ekins s. J Clin Invest. 2022 Oct 17;132(20):e163107. doi: 10.1172/JCI163107. J Clin Invest. 2022. PMID: 36040802 Free PMC article.
Machine Learning Models Identify New Inhibitors for Human OATP1B1.
Lane TR, Urbina F, Zhang X, Fye M, Gerlach J, Wright SH, Ekins S. Lane TR, et al. Among authors: ekins s. Mol Pharm. 2022 Nov 7;19(11):4320-4332. doi: 10.1021/acs.molpharmaceut.2c00662. Epub 2022 Oct 21. Mol Pharm. 2022. PMID: 36269563 Free PMC article.
376 results