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The role of GIP in α-cells and glucagon secretion.
El K, Campbell JE. El K, et al. Peptides. 2020 Mar;125:170213. doi: 10.1016/j.peptides.2019.170213. Epub 2019 Nov 27. Peptides. 2020. PMID: 31785304 Free PMC article. Review.
Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells.
Gray SM, Xin Y, Ross EC, Chazotte BM, Capozzi ME, El K, Svendsen B, Ravn P, Sloop KW, Tong J, Gromada J, Campbell JE, D'Alessio DA. Gray SM, et al. Among authors: el k. J Biol Chem. 2020 Aug 14;295(33):11529-11541. doi: 10.1074/jbc.RA120.014368. Epub 2020 Jun 18. J Biol Chem. 2020. PMID: 32554468 Free PMC article.
The ubiquitination status of the glucagon receptor determines signal bias.
Kaur S, Sokrat B, Capozzi ME, El K, Bai Y, Jazic A, Han B, Krishna Kumar K, D'Alessio DA, Campbell JE, Bouvier M, Shenoy SK. Kaur S, et al. Among authors: el k. J Biol Chem. 2023 May;299(5):104690. doi: 10.1016/j.jbc.2023.104690. Epub 2023 Apr 8. J Biol Chem. 2023. PMID: 37037304 Free PMC article.
Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding.
Adriaenssens A, Broichhagen J, de Bray A, Ast J, Hasib A, Jones B, Tomas A, Burgos NF, Woodward O, Lewis J, O'Flaherty E, El K, Cui C, Harada N, Inagaki N, Campbell J, Brierley D, Hodson DJ, Samms R, Gribble F, Reimann F. Adriaenssens A, et al. Among authors: el k. JCI Insight. 2023 May 22;8(10):e164921. doi: 10.1172/jci.insight.164921. JCI Insight. 2023. PMID: 37212283 Free PMC article.
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets.
El K, Douros JD, Willard FS, Novikoff A, Sargsyan A, Perez-Tilve D, Wainscott DB, Yang B, Chen A, Wothe D, Coupland C, Tschöp MH, Finan B, D'Alessio DA, Sloop KW, Müller TD, Campbell JE. El K, et al. Nat Metab. 2023 Jun;5(6):945-954. doi: 10.1038/s42255-023-00811-0. Epub 2023 Jun 5. Nat Metab. 2023. PMID: 37277609 Free PMC article.
31 results