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Alterations in Sub-Axonal Architecture Between Normal Aging and Parkinson's Diseased Human Brains Using Label-Free Cryogenic X-ray Nanotomography.
Tran HT, Tsai EHR, Lewis AJ, Moors T, Bol JGJM, Rostami I, Diaz A, Jonker AJ, Guizar-Sicairos M, Raabe J, Stahlberg H, van de Berg WDJ, Holler M, Shahmoradian SH. Tran HT, et al. Among authors: shahmoradian sh. Front Neurosci. 2020 Nov 25;14:570019. doi: 10.3389/fnins.2020.570019. eCollection 2020. Front Neurosci. 2020. PMID: 33324142 Free PMC article.
Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles.
Navarro PP, Genoud C, Castaño-Díez D, Graff-Meyer A, Lewis AJ, de Gier Y, Lauer ME, Britschgi M, Bohrmann B, Frank S, Hench J, Schweighauser G, Rozemuller AJM, van de Berg WDJ, Stahlberg H, Shahmoradian SH. Navarro PP, et al. Among authors: shahmoradian sh. Sci Rep. 2018 Dec 21;8(1):18046. doi: 10.1038/s41598-018-36223-4. Sci Rep. 2018. PMID: 30575769 Free PMC article.
Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes.
Shahmoradian SH, Lewis AJ, Genoud C, Hench J, Moors TE, Navarro PP, Castaño-Díez D, Schweighauser G, Graff-Meyer A, Goldie KN, Sütterlin R, Huisman E, Ingrassia A, Gier Y, Rozemuller AJM, Wang J, Paepe A, Erny J, Staempfli A, Hoernschemeyer J, Großerüschkamp F, Niedieker D, El-Mashtoly SF, Quadri M, Van IJcken WFJ, Bonifati V, Gerwert K, Bohrmann B, Frank S, Britschgi M, Stahlberg H, Van de Berg WDJ, Lauer ME. Shahmoradian SH, et al. Nat Neurosci. 2019 Jul;22(7):1099-1109. doi: 10.1038/s41593-019-0423-2. Epub 2019 Jun 24. Nat Neurosci. 2019. PMID: 31235907
Imaging of post-mortem human brain tissue using electron and X-ray microscopy.
Lewis AJ, Genoud C, Pont M, van de Berg WD, Frank S, Stahlberg H, Shahmoradian SH, Al-Amoudi A. Lewis AJ, et al. Among authors: shahmoradian sh. Curr Opin Struct Biol. 2019 Oct;58:138-148. doi: 10.1016/j.sbi.2019.06.003. Epub 2019 Jul 23. Curr Opin Struct Biol. 2019. PMID: 31349127 Free article. Review.
TorsinA is essential for neuronal nuclear pore complex localization and maturation.
Kim S, Phan S, Tran HT, Shaw TR, Shahmoradian SH, Ellisman MH, Veatch SL, Barmada SJ, Pappas SS, Dauer WT. Kim S, et al. Among authors: shahmoradian sh. Nat Cell Biol. 2024 Sep;26(9):1482-1495. doi: 10.1038/s41556-024-01480-1. Epub 2024 Aug 8. Nat Cell Biol. 2024. PMID: 39117796 Free PMC article.
21 results