Li W - Search Results

1

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis.

Xu C, Fischer DK, Rankovic S, Li W, Dick RA, Runge B, Zadorozhnyi R, Ahn J, Aiken C, Polenova T, Engelman AN, Ambrose Z, Rousso I, Perilla JR. Xu C, et al. Among authors: li w. PLoS Biol. 2020 Dec 17;18(12):e3001015. doi: 10.1371/journal.pbio.3001015. eCollection 2020 Dec. PLoS Biol. 2020. PMID: 33332391 Free PMC article.

2

Dominant Negative MA-CA Fusion Protein Is Incorporated into HIV-1 Cores and Inhibits Nuclear Entry of Viral Preintegration Complexes.

Anderson-Daniels J, Singh PK, Sowd GA, Li W, Engelman AN, Aiken C. Anderson-Daniels J, et al. Among authors: li w. J Virol. 2019 Oct 15;93(21):e01118-19. doi: 10.1128/JVI.01118-19. Print 2019 Nov 1. J Virol. 2019. PMID: 31413124 Free PMC article.

3

Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.

Ni T, Gerard S, Zhao G, Dent K, Ning J, Zhou J, Shi J, Anderson-Daniels J, Li W, Jang S, Engelman AN, Aiken C, Zhang P. Ni T, et al. Among authors: li w. Nat Struct Mol Biol. 2020 Sep;27(9):855-862. doi: 10.1038/s41594-020-0467-8. Epub 2020 Aug 3. Nat Struct Mol Biol. 2020. PMID: 32747784 Free PMC article.

4

Capsid Lattice Destabilization Leads to Premature Loss of the Viral Genome and Integrase Enzyme during HIV-1 Infection.

Eschbach JE, Elliott JL, Li W, Zadrozny KK, Davis K, Mohammed SJ, Lawson DQ, Pornillos O, Engelman AN, Kutluay SB. Eschbach JE, et al. Among authors: li w. J Virol. 2020 Dec 22;95(2):e00984-20. doi: 10.1128/JVI.00984-20. Print 2020 Dec 22. J Virol. 2020. PMID: 33115869 Free PMC article.

5

Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis.

Elliott JL, Eschbach JE, Koneru PC, Li W, Puray-Chavez M, Townsend D, Lawson DQ, Engelman AN, Kvaratskhelia M, Kutluay SB. Elliott JL, et al. Among authors: li w. Elife. 2020 Sep 22;9:e54311. doi: 10.7554/eLife.54311. Elife. 2020. PMID: 32960169 Free PMC article.

6

rigrag: high-resolution mapping of genic targeting preferences during HIV-1 integration in vitro and in vivo.

Bedwell GJ, Jang S, Li W, Singh PK, Engelman AN. Bedwell GJ, et al. Among authors: li w. Nucleic Acids Res. 2021 Jul 21;49(13):7330-7346. doi: 10.1093/nar/gkab514. Nucleic Acids Res. 2021. PMID: 34165568 Free PMC article.

7

Deep-learning in situ classification of HIV-1 virion morphology.

Rey JS, Li W, Bryer AJ, Beatson H, Lantz C, Engelman AN, Perilla JR. Rey JS, et al. Among authors: li w. Comput Struct Biotechnol J. 2021 Oct 5;19:5688-5700. doi: 10.1016/j.csbj.2021.10.001. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34765089 Free PMC article.

8

HIV-1 integrase binding to genomic RNA 5'-UTR induces local structural changes in vitro and in virio.

Liu S, Koneru PC, Li W, Pathirage C, Engelman AN, Kvaratskhelia M, Musier-Forsyth K. Liu S, et al. Among authors: li w. Retrovirology. 2021 Nov 22;18(1):37. doi: 10.1186/s12977-021-00582-0. Retrovirology. 2021. PMID: 34809662 Free PMC article.

9

Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors.

Singh PK, Li W, Bedwell GJ, Fadel HJ, Poeschla EM, Engelman AN. Singh PK, et al. Among authors: li w. Viruses. 2022 Aug 26;14(9):1883. doi: 10.3390/v14091883. Viruses. 2022. PMID: 36146690 Free PMC article.

10

Structural basis of second-generation HIV integrase inhibitor action and viral resistance.

Cook NJ, Li W, Berta D, Badaoui M, Ballandras-Colas A, Nans A, Kotecha A, Rosta E, Engelman AN, Cherepanov P. Cook NJ, et al. Among authors: li w. Science. 2020 Feb 14;367(6479):806-810. doi: 10.1126/science.aay4919. Epub 2020 Jan 30. Science. 2020. PMID: 32001525 Free PMC article.

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