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Phospholemman Phosphorylation Regulates Vascular Tone, Blood Pressure, and Hypertension in Mice and Humans.
Boguslavskyi A, Tokar S, Prysyazhna O, Rudyk O, Sanchez-Tatay D, Lemmey HAL, Dora KA, Garland CJ, Warren HR, Doney A, Palmer CNA, Caulfield MJ, Vlachaki Walker J, Howie J, Fuller W, Shattock MJ. Boguslavskyi A, et al. Among authors: rudyk o. Circulation. 2021 Mar 16;143(11):1123-1138. doi: 10.1161/CIRCULATIONAHA.119.040557. Epub 2020 Dec 18. Circulation. 2021. PMID: 33334125 Free PMC article.
Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.
Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamas K, Hadgraft N, Martin ED, Worthington J, Rudyk O, Rodriguez Cutillas P, Cuello F, Shattock MJ, Marber MS, Conte MR, Greenstein A, Greensmith DJ, Venetucci L, Timms JF, Eaton P. Scotcher J, et al. Among authors: rudyk o. Nat Commun. 2016 Oct 26;7:13187. doi: 10.1038/ncomms13187. Nat Commun. 2016. PMID: 27782102 Free PMC article.
Protein kinase G oxidation is a major cause of injury during sepsis.
Rudyk O, Phinikaridou A, Prysyazhna O, Burgoyne JR, Botnar RM, Eaton P. Rudyk O, et al. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9909-13. doi: 10.1073/pnas.1301026110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716652 Free PMC article.
Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension.
Rudyk O, Rowan A, Prysyazhna O, Krasemann S, Hartmann K, Zhang M, Shah AM, Ruppert C, Weiss A, Schermuly RT, Ida T, Akaike T, Zhao L, Eaton P. Rudyk O, et al. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13016-13025. doi: 10.1073/pnas.1904064116. Epub 2019 Jun 11. Proc Natl Acad Sci U S A. 2019. PMID: 31186362 Free PMC article.
33 results