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Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy.
Wisdom AJ, Mowery YM, Hong CS, Himes JE, Nabet BY, Qin X, Zhang D, Chen L, Fradin H, Patel R, Bassil AM, Muise ES, King DA, Xu ES, Carpenter DJ, Kent CL, Smythe KS, Williams NT, Luo L, Ma Y, Alizadeh AA, Owzar K, Diehn M, Bradley T, Kirsch DG. Wisdom AJ, et al. Among authors: luo l. Nat Commun. 2020 Dec 17;11(1):6410. doi: 10.1038/s41467-020-19917-0. Nat Commun. 2020. PMID: 33335088 Free PMC article.
MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes.
Sachdeva M, Mito JK, Lee CL, Zhang M, Li Z, Dodd RD, Cason D, Luo L, Ma Y, Van Mater D, Gladdy R, Lev DC, Cardona DM, Kirsch DG. Sachdeva M, et al. Among authors: luo l. J Clin Invest. 2014 Oct;124(10):4305-19. doi: 10.1172/JCI77116. Epub 2014 Sep 2. J Clin Invest. 2014. PMID: 25180607 Free PMC article.
HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism.
Zhang M, Qiu Q, Li Z, Sachdeva M, Min H, Cardona DM, DeLaney TF, Han T, Ma Y, Luo L, Ilkayeva OR, Lui K, Nichols AG, Newgard CB, Kastan MB, Rathmell JC, Dewhirst MW, Kirsch DG. Zhang M, et al. Among authors: luo l. Radiat Res. 2015 Jun;183(6):594-609. doi: 10.1667/RR14016.1. Epub 2015 May 14. Radiat Res. 2015. PMID: 25973951 Free PMC article.
Characterizing the Potency and Impact of Carbon Ion Therapy in a Primary Mouse Model of Soft Tissue Sarcoma.
Brownstein JM, Wisdom AJ, Castle KD, Mowery YM, Guida P, Lee CL, Tommasino F, Tessa C, Scifoni E, Gao J, Luo L, Campos LDS, Ma Y, Williams N, Jung SH, Durante M, Kirsch DG. Brownstein JM, et al. Among authors: luo l. Mol Cancer Ther. 2018 Apr;17(4):858-868. doi: 10.1158/1535-7163.MCT-17-0965. Epub 2018 Feb 7. Mol Cancer Ther. 2018. PMID: 29437879 Free PMC article.
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