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Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors.
Saydmohammed M, Jha A, Mahajan V, Gavlock D, Shun TY, DeBiasio R, Lefever D, Li X, Reese C, Kershaw EE, Yechoor V, Behari J, Soto-Gutierrez A, Vernetti L, Stern A, Gough A, Miedel MT, Lansing Taylor D. Saydmohammed M, et al. Exp Biol Med (Maywood). 2021 Nov;246(22):2420-2441. doi: 10.1177/15353702211009228. Epub 2021 May 6. Exp Biol Med (Maywood). 2021. PMID: 33957803 Free PMC article. Review.
Biofabrication of synthetic human liver tissue with advanced programmable functions.
Florentino RM, Morita K, Haep N, Motomura T, Diaz-Aragon R, Faccioli LAP, Collin de l'Hortet A, Cetin Z, Frau C, Vernetti L, Amler AK, Thomas A, Lam T, Kloke L, Takeishi K, Taylor DL, Fox IJ, Soto-Gutierrez A. Florentino RM, et al. iScience. 2022 Nov 4;25(12):105503. doi: 10.1016/j.isci.2022.105503. eCollection 2022 Dec 22. iScience. 2022. PMID: 36404924 Free PMC article.
A metabolic-dysfunction associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system.
Aleman J, Ravikumar K, Wiegand C, Schurdak ME, Vernetti L, Gavlock D, Reese C, DeBiasio R, LaRocca G, Angarita YD, Gough A, Soto-Gutierrez A, Behari J, Yechoor V, Miedel MT, Stern AM, Banerjee I, Taylor DL. Aleman J, et al. Among authors: soto gutierrez a. bioRxiv [Preprint]. 2024 Apr 30:2024.04.22.590598. doi: 10.1101/2024.04.22.590598. bioRxiv. 2024. Update in: Commun Biol. 2024 Oct 14;7(1):1317. doi: 10.1038/s42003-024-07006-7 PMID: 38712135 Free PMC article. Updated. Preprint.
Assembly of human organs from stem cells to study liver disease.
Handa K, Matsubara K, Fukumitsu K, Guzman-Lepe J, Watson A, Soto-Gutierrez A. Handa K, et al. Am J Pathol. 2014 Feb;184(2):348-57. doi: 10.1016/j.ajpath.2013.11.003. Epub 2013 Dec 12. Am J Pathol. 2014. PMID: 24333262 Free PMC article. Review.
A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease.
Nishikawa T, Bellance N, Damm A, Bing H, Zhu Z, Handa K, Yovchev MI, Sehgal V, Moss TJ, Oertel M, Ram PT, Pipinos II, Soto-Gutierrez A, Fox IJ, Nagrath D. Nishikawa T, et al. J Hepatol. 2014 Jun;60(6):1203-11. doi: 10.1016/j.jhep.2014.02.014. Epub 2014 Feb 26. J Hepatol. 2014. PMID: 24583248 Free PMC article.
Host conditioning and rejection monitoring in hepatocyte transplantation in humans.
Soltys KA, Setoyama K, Tafaleng EN, Soto Gutiérrez A, Fong J, Fukumitsu K, Nishikawa T, Nagaya M, Sada R, Haberman K, Gramignoli R, Dorko K, Tahan V, Dreyzin A, Baskin K, Crowley JJ, Quader MA, Deutsch M, Ashokkumar C, Shneider BL, Squires RH, Ranganathan S, Reyes-Mugica M, Dobrowolski SF, Mazariegos G, Elango R, Stolz DB, Strom SC, Vockley G, Roy-Chowdhury J, Cascalho M, Guha C, Sindhi R, Platt JL, Fox IJ. Soltys KA, et al. J Hepatol. 2017 May;66(5):987-1000. doi: 10.1016/j.jhep.2016.12.017. Epub 2016 Dec 24. J Hepatol. 2017. PMID: 28027971 Free PMC article.
117 results