Aittokallio T - Search Results

1

Systematic mapping of cancer cell target dependencies using high-throughput drug screening in triple-negative breast cancer.

Wang T, Gautam P, Rousu J, Aittokallio T. Wang T, et al. Among authors: aittokallio t. Comput Struct Biotechnol J. 2020 Nov 24;18:3819-3832. doi: 10.1016/j.csbj.2020.11.001. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 33335681 Free PMC article.

2

Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles.

Szwajda A, Gautam P, Karhinen L, Jha SK, Saarela J, Shakyawar S, Turunen L, Yadav B, Tang J, Wennerberg K, Aittokallio T. Szwajda A, et al. Among authors: aittokallio t. Chem Biol. 2015 Aug 20;22(8):1144-55. doi: 10.1016/j.chembiol.2015.06.021. Epub 2015 Jul 23. Chem Biol. 2015. PMID: 26211361

3

Identification of drug candidates and repurposing opportunities through compound-target interaction networks.

Cichonska A, Rousu J, Aittokallio T. Cichonska A, et al. Among authors: aittokallio t. Expert Opin Drug Discov. 2015 Dec;10(12):1333-45. doi: 10.1517/17460441.2015.1096926. Epub 2015 Oct 1. Expert Opin Drug Discov. 2015. PMID: 26429153 Review.

4

Searching for Drug Synergy in Complex Dose-Response Landscapes Using an Interaction Potency Model.

Yadav B, Wennerberg K, Aittokallio T, Tang J. Yadav B, et al. Among authors: aittokallio t. Comput Struct Biotechnol J. 2015 Sep 25;13:504-13. doi: 10.1016/j.csbj.2015.09.001. eCollection 2015. Comput Struct Biotechnol J. 2015. PMID: 26949479 Free PMC article.

5

Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells.

Gautam P, Karhinen L, Szwajda A, Jha SK, Yadav B, Aittokallio T, Wennerberg K. Gautam P, et al. Among authors: aittokallio t. Mol Cancer. 2016 May 10;15(1):34. doi: 10.1186/s12943-016-0517-3. Mol Cancer. 2016. PMID: 27165605 Free PMC article.

6

Consistency in drug response profiling.

Mpindi JP, Yadav B, Östling P, Gautam P, Malani D, Murumägi A, Hirasawa A, Kangaspeska S, Wennerberg K, Kallioniemi O, Aittokallio T. Mpindi JP, et al. Among authors: aittokallio t. Nature. 2016 Nov 30;540(7631):E5-E6. doi: 10.1038/nature20171. Nature. 2016. PMID: 27905421 No abstract available.

7

Computational-experimental approach to drug-target interaction mapping: A case study on kinase inhibitors.

Cichonska A, Ravikumar B, Parri E, Timonen S, Pahikkala T, Airola A, Wennerberg K, Rousu J, Aittokallio T. Cichonska A, et al. Among authors: aittokallio t. PLoS Comput Biol. 2017 Aug 7;13(8):e1005678. doi: 10.1371/journal.pcbi.1005678. eCollection 2017 Aug. PLoS Comput Biol. 2017. PMID: 28787438 Free PMC article.

8

Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions.

Tang J, Tanoli ZU, Ravikumar B, Alam Z, Rebane A, Vähä-Koskela M, Peddinti G, van Adrichem AJ, Wakkinen J, Jaiswal A, Karjalainen E, Gautam P, He L, Parri E, Khan S, Gupta A, Ali M, Yetukuri L, Gustavsson AL, Seashore-Ludlow B, Hersey A, Leach AR, Overington JP, Repasky G, Wennerberg K, Aittokallio T. Tang J, et al. Among authors: aittokallio t. Cell Chem Biol. 2018 Feb 15;25(2):224-229.e2. doi: 10.1016/j.chembiol.2017.11.009. Epub 2017 Dec 21. Cell Chem Biol. 2018. PMID: 29276046 Free PMC article.

9

Learning with multiple pairwise kernels for drug bioactivity prediction.

Cichonska A, Pahikkala T, Szedmak S, Julkunen H, Airola A, Heinonen M, Aittokallio T, Rousu J. Cichonska A, et al. Among authors: aittokallio t. Bioinformatics. 2018 Jul 1;34(13):i509-i518. doi: 10.1093/bioinformatics/bty277. Bioinformatics. 2018. PMID: 29949975 Free PMC article.

10

Corrigendum to "Searching for drug synergy in complex dose-response landscapes using an interaction potency model" [Comput. Struct. Biotechnol. J. 13 (2015) 504-513].

Yadav B, Wennerberg K, Aittokallio T, Tang J. Yadav B, et al. Among authors: aittokallio t. Comput Struct Biotechnol J. 2017 Jul 25;15:387. doi: 10.1016/j.csbj.2017.07.003. eCollection 2017. Comput Struct Biotechnol J. 2017. PMID: 29991977 Free PMC article.

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