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In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection.
Colley T, Alanio A, Kelly SL, Sehra G, Kizawa Y, Warrilow AGS, Parker JE, Kelly DE, Kimura G, Anderson-Dring L, Nakaoki T, Sunose M, Onions S, Crepin D, Lagasse F, Crittall M, Shannon J, Cooke M, Bretagne S, King-Underwood J, Murray J, Ito K, Strong P, Rapeport G. Colley T, et al. Among authors: rapeport g. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02280-16. doi: 10.1128/AAC.02280-16. Print 2017 May. Antimicrob Agents Chemother. 2017. PMID: 28223388 Free PMC article.
Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.
Brookes DW, Coates M, Allen H, Daly L, Constant S, Huang S, Hows M, Davis A, Cass L, Ayrton J, Knowles I, Strong P, Rapeport G, Ito K. Brookes DW, et al. Among authors: rapeport g. Br J Pharmacol. 2018 Jun;175(12):2520-2534. doi: 10.1111/bph.14221. Epub 2018 May 2. Br J Pharmacol. 2018. PMID: 29579332 Free PMC article.
Current approaches to the discovery of novel inhaled medicines.
Strong P, Ito K, Murray J, Rapeport G. Strong P, et al. Among authors: rapeport g. Drug Discov Today. 2018 Oct;23(10):1705-1717. doi: 10.1016/j.drudis.2018.05.017. Epub 2018 May 20. Drug Discov Today. 2018. PMID: 29775668 Free article. Review.
In Vitro and In Vivo Efficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, on Aspergillus fumigatus Infection.
Colley T, Sehra G, Chowdhary A, Alanio A, Kelly SL, Kizawa Y, Armstrong-James D, Fisher MC, Warrilow AGS, Parker JE, Kelly DE, Kimura G, Nishimoto Y, Sunose M, Onions S, Crepin D, Lagasse F, Crittall M, Shannon J, McConville M, King-Underwood J, Naylor A, Bretagne S, Murray J, Ito K, Strong P, Rapeport G. Colley T, et al. Among authors: rapeport g. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e01941-17. doi: 10.1128/AAC.01941-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29439966 Free PMC article.
24 results