Litwak S - Search Results

1

The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice.

Ge T, Jhala G, Fynch S, Akazawa S, Litwak S, Pappas EG, Catterall T, Vakil I, Long AJ, Olson LM, Krishnamurthy B, Kay TW, Thomas HE. Ge T, et al. Among authors: litwak s. Front Immunol. 2020 Dec 4;11:588543. doi: 10.3389/fimmu.2020.588543. eCollection 2020. Front Immunol. 2020. PMID: 33343569 Free PMC article.

2

Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets.

Stanley WJ, Litwak SA, Quah HS, Tan SM, Kay TW, Tiganis T, de Haan JB, Thomas HE, Gurzov EN. Stanley WJ, et al. Diabetes. 2015 Jul;64(7):2489-96. doi: 10.2337/db14-1575. Epub 2015 Mar 2. Diabetes. 2015. PMID: 25732191

3

Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System.

Litwak SA, Wali JA, Pappas EG, Saadi H, Stanley WJ, Varanasi LC, Kay TW, Thomas HE, Gurzov EN. Litwak SA, et al. J Diabetes Res. 2015;2015:280615. doi: 10.1155/2015/280615. Epub 2015 May 6. J Diabetes Res. 2015. PMID: 26064977 Free PMC article.

4

p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.

Litwak SA, Loh K, Stanley WJ, Pappas EG, Wali JA, Selck C, Strasser A, Thomas HE, Gurzov EN. Litwak SA, et al. Sci Rep. 2016 Apr 1;6:23802. doi: 10.1038/srep23802. Sci Rep. 2016. PMID: 27033313 Free PMC article.

5

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.

Litwak SA, Pang L, Galic S, Igoillo-Esteve M, Stanley WJ, Turatsinze JV, Loh K, Thomas HE, Sharma A, Trepo E, Moreno C, Gough DJ, Eizirik DL, de Haan JB, Gurzov EN. Litwak SA, et al. Diabetes. 2017 Dec;66(12):2973-2986. doi: 10.2337/db17-0348. Epub 2017 Sep 19. Diabetes. 2017. PMID: 28928277

6

STAT3 Regulates Mitochondrial Gene Expression in Pancreatic β-Cells and Its Deficiency Induces Glucose Intolerance in Obesity.

Schaschkow A, Pang L, Vandenbempt V, Elvira B, Litwak SA, Vekeriotaite B, Maillard E, Vermeersch M, Paula FMM, Pinget M, Perez-Morga D, Gough DJ, Gurzov EN. Schaschkow A, et al. Among authors: litwak sa. Diabetes. 2021 Sep;70(9):2026-2041. doi: 10.2337/db20-1222. Epub 2021 Jun 28. Diabetes. 2021. PMID: 34183374

7

Pancreatic β-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species.

Pilkington EH, Gurzov EN, Kakinen A, Litwak SA, Stanley WJ, Davis TP, Ke PC. Pilkington EH, et al. Among authors: litwak sa. Sci Rep. 2016 Feb 16;6:21274. doi: 10.1038/srep21274. Sci Rep. 2016. PMID: 26880502 Free PMC article.

8

Insulin-Binding Peptide Probes Provide a Novel Strategy for Pancreatic β-Cell Imaging.

Eriksson M, Litwak SA, Yun Y, Stanley WJ, Thorn P, Ahlgren U, Gurzov EN. Eriksson M, et al. Among authors: litwak sa. Mol Pharm. 2021 Dec 6;18(12):4428-4436. doi: 10.1021/acs.molpharmaceut.1c00616. Epub 2021 Oct 14. Mol Pharm. 2021. PMID: 34649437

9

Inhibition of hIAPP Amyloid Aggregation and Pancreatic β-Cell Toxicity by OH-Terminated PAMAM Dendrimer.

Gurzov EN, Wang B, Pilkington EH, Chen P, Kakinen A, Stanley WJ, Litwak SA, Hanssen EG, Davis TP, Ding F, Ke PC. Gurzov EN, et al. Small. 2016 Mar 23;12(12):1615-26. doi: 10.1002/smll.201502317. Epub 2016 Jan 25. Small. 2016. PMID: 26808649 Free article.

10

Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells.

Nedumpully-Govindan P, Gurzov EN, Chen P, Pilkington EH, Stanley WJ, Litwak SA, Davis TP, Ke PC, Ding F. Nedumpully-Govindan P, et al. Phys Chem Chem Phys. 2016 Jan 7;18(1):94-100. doi: 10.1039/c5cp05924k. Epub 2015 Dec 2. Phys Chem Chem Phys. 2016. PMID: 26625841 Free PMC article.

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