Xu M - Search Results

1

The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules.

Gorshkov K, Chen CZ, Bostwick R, Rasmussen L, Tran BN, Cheng YS, Xu M, Pradhan M, Henderson M, Zhu W, Oh E, Susumu K, Wolak M, Shamim K, Huang W, Hu X, Shen M, Klumpp-Thomas C, Itkin Z, Shinn P, Carlos de la Torre J, Simeonov A, Michael SG, Hall MD, Lo DC, Zheng W. Gorshkov K, et al. Among authors: xu m. ACS Infect Dis. 2021 Jun 11;7(6):1389-1408. doi: 10.1021/acsinfecdis.0c00349. Epub 2020 Dec 21. ACS Infect Dis. 2021. PMID: 33346633 Free PMC article.

2

A high-throughput sphingomyelinase assay using natural substrate.

Xu M, Liu K, Southall N, Marugan JJ, Remaley AT, Zheng W. Xu M, et al. Anal Bioanal Chem. 2012 Aug;404(2):407-14. doi: 10.1007/s00216-012-6174-5. Epub 2012 Jun 19. Anal Bioanal Chem. 2012. PMID: 22710568 Free PMC article.

3

δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders.

Xu M, Liu K, Swaroop M, Porter FD, Sidhu R, Firnkes S, Ory DS, Marugan JJ, Xiao J, Southall N, Pavan WJ, Davidson C, Walkley SU, Remaley AT, Baxa U, Sun W, McKew JC, Austin CP, Zheng W. Xu M, et al. J Biol Chem. 2012 Nov 16;287(47):39349-60. doi: 10.1074/jbc.M112.357707. Epub 2012 Oct 3. J Biol Chem. 2012. PMID: 23035117 Free PMC article.

4

A phenotypic compound screening assay for lysosomal storage diseases.

Xu M, Liu K, Swaroop M, Sun W, Dehdashti SJ, McKew JC, Zheng W. Xu M, et al. J Biomol Screen. 2014 Jan;19(1):168-75. doi: 10.1177/1087057113501197. Epub 2013 Aug 27. J Biomol Screen. 2014. PMID: 23983233 Free PMC article.

5

Disease models for the development of therapies for lysosomal storage diseases.

Xu M, Motabar O, Ferrer M, Marugan JJ, Zheng W, Ottinger EA. Xu M, et al. Ann N Y Acad Sci. 2016 May;1371(1):15-29. doi: 10.1111/nyas.13052. Epub 2016 May 4. Ann N Y Acad Sci. 2016. PMID: 27144735 Free PMC article. Review.

6

Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A.

Long Y, Xu M, Li R, Dai S, Beers J, Chen G, Soheilian F, Baxa U, Wang M, Marugan JJ, Muro S, Li Z, Brady R, Zheng W. Long Y, et al. Among authors: xu m. Stem Cells Transl Med. 2016 Dec;5(12):1644-1655. doi: 10.5966/sctm.2015-0373. Epub 2016 Aug 2. Stem Cells Transl Med. 2016. PMID: 27484861 Free PMC article.

7

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.

Xu M, Lee EM, Wen Z, Cheng Y, Huang WK, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael SG, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H. Xu M, et al. Nat Med. 2016 Oct;22(10):1101-1107. doi: 10.1038/nm.4184. Epub 2016 Aug 29. Nat Med. 2016. PMID: 27571349 Free PMC article.

8

High throughput cell-based assay for identification of glycolate oxidase inhibitors as a potential treatment for Primary Hyperoxaluria Type 1.

Wang M, Xu M, Long Y, Fargue S, Southall N, Hu X, McKew JC, Danpure CJ, Zheng W. Wang M, et al. Among authors: xu m. Sci Rep. 2016 Sep 27;6:34060. doi: 10.1038/srep34060. Sci Rep. 2016. PMID: 27670739 Free PMC article.

9

A High-Throughput Assay for Developing Inhibitors of PhoP, a Virulence Factor of Mycobacterium tuberculosis.

Wang L, Xu M, Southall N, Zheng W, Wang S. Wang L, et al. Among authors: xu m. Comb Chem High Throughput Screen. 2016;19(10):855-864. doi: 10.2174/1386207319666161010163249. Comb Chem High Throughput Screen. 2016. PMID: 27748178 Free PMC article.

10

Rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria.

Sun W, Weingarten RA, Xu M, Southall N, Dai S, Shinn P, Sanderson PE, Williamson PR, Frank KM, Zheng W. Sun W, et al. Among authors: xu m. Emerg Microbes Infect. 2016 Nov 9;5(11):e116. doi: 10.1038/emi.2016.123. Emerg Microbes Infect. 2016. PMID: 27826141 Free PMC article.

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