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Interaction with Ribosomal Proteins Accompanies Stress Induction of the Anticancer Metallodrug BOLD-100/KP1339 in the Endoplasmic Reticulum.
Neuditschko B, Legin AA, Baier D, Schintlmeister A, Reipert S, Wagner M, Keppler BK, Berger W, Meier-Menches SM, Gerner C. Neuditschko B, et al. Among authors: gerner c. Angew Chem Int Ed Engl. 2021 Mar 1;60(10):5063-5068. doi: 10.1002/anie.202015962. Epub 2021 Feb 1. Angew Chem Int Ed Engl. 2021. PMID: 33369073 Free PMC article.
EGCG-meditated cyto- and genotoxicity in HaCat keratinocytes is impaired by cell-mediated clearance of auto-oxidation-derived H2O2: an algorithm for experimental setting correction.
Elbling L, Herbacek I, Weiss RM, Gerner C, Heffeter P, Jantschitsch C, Trautinger F, Grusch M, Pangratz H, Berger W. Elbling L, et al. Among authors: gerner c. Toxicol Lett. 2011 Aug 28;205(2):173-82. doi: 10.1016/j.toxlet.2011.06.001. Epub 2011 Jun 15. Toxicol Lett. 2011. PMID: 21704138
An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin.
Meier SM, Kreutz D, Winter L, Klose MHM, Cseh K, Weiss T, Bileck A, Alte B, Mader JC, Jana S, Chatterjee A, Bhattacharyya A, Hejl M, Jakupec MA, Heffeter P, Berger W, Hartinger CG, Keppler BK, Wiche G, Gerner C. Meier SM, et al. Among authors: gerner c. Angew Chem Int Ed Engl. 2017 Jul 3;56(28):8267-8271. doi: 10.1002/anie.201702242. Epub 2017 May 26. Angew Chem Int Ed Engl. 2017. PMID: 28547791
Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis.
Schoenhacker-Alte B, Mohr T, Pirker C, Kryeziu K, Kuhn PS, Buck A, Hofmann T, Gerner C, Hermann G, Koellensperger G, Keppler BK, Berger W, Heffeter P. Schoenhacker-Alte B, et al. Among authors: gerner c. Cancer Lett. 2017 Sep 28;404:79-88. doi: 10.1016/j.canlet.2017.07.009. Epub 2017 Jul 14. Cancer Lett. 2017. PMID: 28716523
Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
Mayer RL, Schwarzmeier JD, Gerner MC, Bileck A, Mader JC, Meier-Menches SM, Gerner SM, Schmetterer KG, Pukrop T, Reichle A, Slany A, Gerner C. Mayer RL, et al. Among authors: gerner mc, gerner sm, gerner c. Mol Cell Proteomics. 2018 Feb;17(2):290-303. doi: 10.1074/mcp.RA117.000425. Epub 2017 Dec 1. Mol Cell Proteomics. 2018. PMID: 29196338 Free PMC article.
225 results