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Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
Konecny J, Misiachna A, Hrabinova M, Pulkrabkova L, Benkova M, Prchal L, Kucera T, Kobrlova T, Finger V, Kolcheva M, Kortus S, Jun D, Valko M, Horak M, Soukup O, Korabecny J. Konecny J, et al. Biomolecules. 2020 Dec 22;11(1):3. doi: 10.3390/biom11010003. Biomolecules. 2020. PMID: 33375115 Free PMC article.
Orexin supplementation in narcolepsy treatment: A review.
Nepovimova E, Janockova J, Misik J, Kubik S, Stuchlik A, Vales K, Korabecny J, Mezeiova E, Dolezal R, Soukup O, Kobrlova T, Pham NL, Nguyen TD, Konecny J, Kuca K. Nepovimova E, et al. Among authors: konecny j. Med Res Rev. 2019 May;39(3):961-975. doi: 10.1002/med.21550. Epub 2018 Nov 14. Med Res Rev. 2019. PMID: 30426515 Review.
Neurotoxicity evoked by organophosphates and available countermeasures.
Pulkrabkova L, Svobodova B, Konecny J, Kobrlova T, Muckova L, Janousek J, Pejchal J, Korabecny J, Soukup O. Pulkrabkova L, et al. Among authors: konecny j. Arch Toxicol. 2023 Jan;97(1):39-72. doi: 10.1007/s00204-022-03397-w. Epub 2022 Nov 6. Arch Toxicol. 2023. PMID: 36335468 Review.
Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition.
Misiachna A, Konecny J, Kolcheva M, Ladislav M, Prchal L, Netolicky J, Kortus S, Zahumenska P, Langore E, Novak M, Hemelikova K, Hermanova Z, Hrochova M, Pelikanova A, Odvarkova J, Pejchal J, Kassa J, Zdarova Karasova J, Korabecny J, Soukup O, Horak M. Misiachna A, et al. Among authors: konecny j. Biomed Pharmacother. 2024 Sep;178:117201. doi: 10.1016/j.biopha.2024.117201. Epub 2024 Jul 24. Biomed Pharmacother. 2024. PMID: 39053419 Free article.
Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects.
Konecny J, Misiachna A, Chvojkova M, Kleteckova L, Kolcheva M, Novak M, Prchal L, Ladislav M, Hemelikova K, Netolicky J, Hrabinova M, Kobrlova T, Karasova JZ, Pejchal J, Fibigar J, Vecera Z, Kucera T, Jendelova P, Zahumenska P, Langore E, Doderovic J, Pang YP, Vales K, Korabecny J, Soukup O, Horak M. Konecny J, et al. Eur J Med Chem. 2024 Dec 15;280:116981. doi: 10.1016/j.ejmech.2024.116981. Epub 2024 Oct 18. Eur J Med Chem. 2024. PMID: 39442339 Free article.
73 results