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Page 1
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
Konecny J, Misiachna A, Hrabinova M, Pulkrabkova L, Benkova M, Prchal L, Kucera T, Kobrlova T, Finger V, Kolcheva M, Kortus S, Jun D, Valko M, Horak M, Soukup O, Korabecny J. Konecny J, et al. Among authors: pulkrabkova l. Biomolecules. 2020 Dec 22;11(1):3. doi: 10.3390/biom11010003. Biomolecules. 2020. PMID: 33375115 Free PMC article.
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole.
Juza R, Stefkova K, Dehaen W, Randakova A, Petrasek T, Vojtechova I, Kobrlova T, Pulkrabkova L, Muckova L, Mecava M, Prchal L, Mezeiova E, Musilek K, Soukup O, Korabecny J. Juza R, et al. Among authors: pulkrabkova l. Biomolecules. 2021 Aug 24;11(9):1262. doi: 10.3390/biom11091262. Biomolecules. 2021. PMID: 34572475 Free PMC article.
N-substituted arylhydroxamic acids as acetylcholinesterase reactivators.
Bondar D, Kapitanov IV, Pulkrabkova L, Soukup O, Jun D, Botelho FD, França TCC, Kuča K, Karpichev Y. Bondar D, et al. Among authors: pulkrabkova l. Chem Biol Interact. 2022 Sep 25;365:110078. doi: 10.1016/j.cbi.2022.110078. Epub 2022 Aug 5. Chem Biol Interact. 2022. PMID: 35940282
Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy.
Perone R, Albertini C, Uliassi E, Di Pietri F, de Sena Murteira Pinheiro P, Petralla S, Rizzardi N, Fato R, Pulkrabkova L, Soukup O, Tramarin A, Bartolini M, Bolognesi ML. Perone R, et al. Among authors: pulkrabkova l. ChemMedChem. 2021 Jan 8;16(1):187-198. doi: 10.1002/cmdc.202000484. Epub 2020 Aug 31. ChemMedChem. 2021. PMID: 32716144
Corrigendum to "Synthesis and broad-spectrum biocidal effect of novel gemini quaternary ammonium compounds" [Bioorg Chem. 151 (2024) 107646].
Zivna N, Hympanova M, Dolezal R, Markova A, Pulkrabkova L, Strakova H, Sleha R, Prchal L, Brozkova I, Motkova P, Šefránková L, Soukup O, Marek J. Zivna N, et al. Among authors: pulkrabkova l. Bioorg Chem. 2024 Dec;153:107844. doi: 10.1016/j.bioorg.2024.107844. Epub 2024 Sep 28. Bioorg Chem. 2024. PMID: 39343621 No abstract available.
Carltonine-derived compounds for targeted butyrylcholinesterase inhibition.
Pidany F, Kroustkova J, Jenco J, Breiterova KH, Muckova L, Novakova L, Kunes J, Fibigar J, Kucera T, Novak M, Sorf A, Hrabinova M, Pulkrabkova L, Janousek J, Soukup O, Jun D, Korabecny J, Cahlikova L. Pidany F, et al. Among authors: pulkrabkova l. RSC Med Chem. 2024 Mar 22;15(5):1601-1625. doi: 10.1039/d4md00060a. eCollection 2024 May 22. RSC Med Chem. 2024. PMID: 38784455 Free PMC article.
Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease.
Mezeiova E, Prchal L, Hrabinova M, Muckova L, Pulkrabkova L, Soukup O, Misiachna A, Janousek J, Fibigar J, Kucera T, Horak M, Makhaeva GF, Korabecny J. Mezeiova E, et al. Among authors: pulkrabkova l. Biomed Pharmacother. 2024 Apr;173:116399. doi: 10.1016/j.biopha.2024.116399. Epub 2024 Mar 15. Biomed Pharmacother. 2024. PMID: 38492439 Free article.
14 results