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A decrease in plasma glucose levels is required for increased endogenous glucose production with a single administration of a sodium-glucose co-transporter-2 inhibitor tofogliflozin.
Yamasaki N, Tamura Y, Kaga H, Sato M, Kiya M, Kadowaki S, Suzuki R, Furukawa Y, Sugimoto D, Funayama T, Someya Y, Kakehi S, Nojiri S, Satoh H, Kawamori R, Watada H. Yamasaki N, et al. Among authors: kakehi s. Diabetes Obes Metab. 2021 May;23(5):1092-1100. doi: 10.1111/dom.14312. Epub 2021 Jan 19. Diabetes Obes Metab. 2021. PMID: 33377253
Increased systemic glucose tolerance with increased muscle glucose uptake in transgenic mice overexpressing RXRγ in skeletal muscle.
Sugita S, Kamei Y, Akaike F, Suganami T, Kanai S, Hattori M, Manabe Y, Fujii N, Takai-Igarashi T, Tadaishi M, Oka J, Aburatani H, Yamada T, Katagiri H, Kakehi S, Tamura Y, Kubo H, Nishida K, Miura S, Ezaki O, Ogawa Y. Sugita S, et al. Among authors: kakehi s. PLoS One. 2011;6(5):e20467. doi: 10.1371/journal.pone.0020467. Epub 2011 May 31. PLoS One. 2011. PMID: 21655215 Free PMC article.
Exercise-induced enhancement of insulin sensitivity is associated with accumulation of M2-polarized macrophages in mouse skeletal muscle.
Ikeda S, Tamura Y, Kakehi S, Takeno K, Kawaguchi M, Watanabe T, Sato F, Ogihara T, Kanazawa A, Fujitani Y, Kawamori R, Watada H. Ikeda S, et al. Among authors: kakehi s. Biochem Biophys Res Commun. 2013 Nov 8;441(1):36-41. doi: 10.1016/j.bbrc.2013.10.005. Epub 2013 Oct 10. Biochem Biophys Res Commun. 2013. PMID: 24120496
Association between expression of FABPpm in skeletal muscle and insulin sensitivity in intramyocellular lipid-accumulated nonobese men.
Kawaguchi M, Tamura Y, Kakehi S, Takeno K, Sakurai Y, Watanabe T, Funayama T, Sato F, Ikeda S, Ogura Y, Saga N, Naito H, Fujitani Y, Kanazawa A, Kawamori R, Watada H. Kawaguchi M, et al. Among authors: kakehi s. J Clin Endocrinol Metab. 2014 Sep;99(9):3343-52. doi: 10.1210/jc.2014-1896. Epub 2014 Jun 17. J Clin Endocrinol Metab. 2014. PMID: 24937540
Effects of sitagliptin on ectopic fat contents and glucose metabolism in type 2 diabetic patients with fatty liver: A pilot study.
Watanabe T, Tamura Y, Kakehi S, Funayama T, Gastaldelli A, Takeno K, Kawaguchi M, Yamamoto R, Sato F, Ikeda S, Taka H, Fujimura T, Fujitani Y, Kawamori R, Watada H. Watanabe T, et al. Among authors: kakehi s. J Diabetes Investig. 2015 Mar;6(2):164-72. doi: 10.1111/jdi.12262. Epub 2014 Aug 6. J Diabetes Investig. 2015. PMID: 25802724 Free PMC article.
Increased intramyocellular lipid/impaired insulin sensitivity is associated with altered lipid metabolic genes in muscle of high responders to a high-fat diet.
Kakehi S, Tamura Y, Takeno K, Sakurai Y, Kawaguchi M, Watanabe T, Funayama T, Sato F, Ikeda S, Kanazawa A, Fujitani Y, Kawamori R, Watada H. Kakehi S, et al. Am J Physiol Endocrinol Metab. 2016 Jan 1;310(1):E32-40. doi: 10.1152/ajpendo.00220.2015. Epub 2015 Oct 20. Am J Physiol Endocrinol Metab. 2016. PMID: 26487001 Free article. Clinical Trial.
Relation Between Insulin Sensitivity and Metabolic Abnormalities in Japanese Men With BMI of 23-25 kg/m2.
Takeno K, Tamura Y, Kawaguchi M, Kakehi S, Watanabe T, Funayama T, Furukawa Y, Kaga H, Yamamoto R, Kim M, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Taka H, Fujimura T, Sawada SS, Giacca A, Kanazawa A, Fujitani Y, Kawamori R, Watada H. Takeno K, et al. Among authors: kakehi s. J Clin Endocrinol Metab. 2016 Oct;101(10):3676-3684. doi: 10.1210/jc.2016-1650. Epub 2016 Jul 6. J Clin Endocrinol Metab. 2016. PMID: 27383116
85 results