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Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).
Yang H, Lundbäck P, Ottosson L, Erlandsson-Harris H, Venereau E, Bianchi ME, Al-Abed Y, Andersson U, Tracey KJ, Antoine DJ. Yang H, et al. Among authors: lundback p. Mol Med. 2012 Mar 30;18(1):250-9. doi: 10.2119/molmed.2011.00389. Mol Med. 2012. Retraction in: Mol Med. 2020 Dec 30;26(1):133. doi: 10.1186/s10020-020-00264-1. PMID: 22105604 Free PMC article. Retracted.
MD-2 is required for disulfide HMGB1-dependent TLR4 signaling.
Yang H, Wang H, Ju Z, Ragab AA, Lundbäck P, Long W, Valdes-Ferrer SI, He M, Pribis JP, Li J, Lu B, Gero D, Szabo C, Antoine DJ, Harris HE, Golenbock DT, Meng J, Roth J, Chavan SS, Andersson U, Billiar TR, Tracey KJ, Al-Abed Y. Yang H, et al. Among authors: lundback p. J Exp Med. 2015 Jan 12;212(1):5-14. doi: 10.1084/jem.20141318. Epub 2015 Jan 5. J Exp Med. 2015. PMID: 25559892 Free PMC article.
A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice.
Lundbäck P, Lea JD, Sowinska A, Ottosson L, Fürst CM, Steen J, Aulin C, Clarke JI, Kipar A, Klevenvall L, Yang H, Palmblad K, Park BK, Tracey KJ, Blom AM, Andersson U, Antoine DJ, Erlandsson Harris H. Lundbäck P, et al. Hepatology. 2016 Nov;64(5):1699-1710. doi: 10.1002/hep.28736. Epub 2016 Sep 1. Hepatology. 2016. PMID: 27474782 Free PMC article.
Novel role of PKR in inflammasome activation and HMGB1 release.
Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ. Lu B, et al. Among authors: lundback p. Nature. 2012 Aug 30;488(7413):670-4. doi: 10.1038/nature11290. Nature. 2012. PMID: 22801494 Free PMC article.
20 results