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In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics.
Xu H, O'Reilly M, Gibbons GS, Changolkar L, McBride JD, Riddle DM, Zhang B, Stieber A, Nirschl J, Kim SJ, Hoxha KH, Brunden KR, Schellenberg GD, Trojanowski JQ, Lee VM. Xu H, et al. Among authors: mcbride jd. Acta Neuropathol. 2021 Feb;141(2):193-215. doi: 10.1007/s00401-020-02253-4. Epub 2021 Jan 1. Acta Neuropathol. 2021. PMID: 33385254 Free PMC article.
A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank.
Toledo JB, Van Deerlin VM, Lee EB, Suh E, Baek Y, Robinson JL, Xie SX, McBride J, Wood EM, Schuck T, Irwin DJ, Gross RG, Hurtig H, McCluskey L, Elman L, Karlawish J, Schellenberg G, Chen-Plotkin A, Wolk D, Grossman M, Arnold SE, Shaw LM, Lee VM, Trojanowski JQ. Toledo JB, et al. Alzheimers Dement. 2014 Jul;10(4):477-484.e1. doi: 10.1016/j.jalz.2013.06.003. Epub 2013 Aug 24. Alzheimers Dement. 2014. PMID: 23978324 Free PMC article.
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology.
Portelius E, Olsson B, Höglund K, Cullen NC, Kvartsberg H, Andreasson U, Zetterberg H, Sandelius Å, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, Elman L, McBride J, Toledo JB, Trojanowski JQ, Blennow K. Portelius E, et al. Acta Neuropathol. 2018 Sep;136(3):363-376. doi: 10.1007/s00401-018-1851-x. Epub 2018 Apr 26. Acta Neuropathol. 2018. PMID: 29700597 Free PMC article.
Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology.
Sandelius Å, Portelius E, Källén Å, Zetterberg H, Rot U, Olsson B, Toledo JB, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, Elman L, Kostanjevecki V, Vandijck M, McBride J, Trojanowski JQ, Blennow K. Sandelius Å, et al. Alzheimers Dement. 2019 Jan;15(1):55-64. doi: 10.1016/j.jalz.2018.08.006. Epub 2018 Oct 12. Alzheimers Dement. 2019. PMID: 30321501 Free PMC article.
61 results