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An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.
Wang L, Balmat TJ, Antonia AL, Constantine FJ, Henao R, Burke TW, Ingham A, McClain MT, Tsalik EL, Ko ER, Ginsburg GS, DeLong MR, Shen X, Woods CW, Hauser ER, Ko DC. Wang L, et al. medRxiv [Preprint]. 2020 Dec 22:2020.12.20.20248572. doi: 10.1101/2020.12.20.20248572. medRxiv. 2020. Update in: Genome Med. 2021 May 17;13(1):83. doi: 10.1186/s13073-021-00904-z PMID: 33398303 Free PMC article. Updated. Preprint.
Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis.
Wang L, Ko ER, Gilchrist JJ, Pittman KJ, Rautanen A, Pirinen M, Thompson JW, Dubois LG, Langley RJ, Jaslow SL, Salinas RE, Rouse DC, Moseley MA, Mwarumba S, Njuguna P, Mturi N; Wellcome Trust Case Control Consortium 2; Kenyan Bacteraemia Study Group; Williams TN, Scott JA, Hill AV, Woods CW, Ginsburg GS, Tsalik EL, Ko DC. Wang L, et al. Sci Adv. 2017 Mar 8;3(3):e1602096. doi: 10.1126/sciadv.1602096. eCollection 2017 Mar. Sci Adv. 2017. PMID: 28345042 Free PMC article. Clinical Trial.
An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease.
Wang L, Pittman KJ, Barker JR, Salinas RE, Stanaway IB, Williams GD, Carroll RJ, Balmat T, Ingham A, Gopalakrishnan AM, Gibbs KD, Antonia AL; eMERGE Network; Heitman J, Lee SC, Jarvik GP, Denny JC, Horner SM, DeLong MR, Valdivia RH, Crosslin DR, Ko DC. Wang L, et al. Cell Host Microbe. 2018 Aug 8;24(2):308-323.e6. doi: 10.1016/j.chom.2018.07.007. Cell Host Microbe. 2018. PMID: 30092202 Free PMC article.
146,326 results
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