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Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits.
Ho WY, Agrawal I, Tyan SH, Sanford E, Chang WT, Lim K, Ong J, Tan BSY, Moe AAK, Yu R, Wong P, Tucker-Kellogg G, Koo E, Chuang KH, Ling SC. Ho WY, et al. Among authors: agrawal i. Acta Neuropathol Commun. 2021 Jan 6;9(1):9. doi: 10.1186/s40478-020-01111-4. Acta Neuropathol Commun. 2021. PMID: 33407930 Free PMC article.
Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction.
Peng AYT, Agrawal I, Ho WY, Yen YC, Pinter AJ, Liu J, Phua QXC, Koh KB, Chang JC, Sanford E, Man JHK, Wong P, Gutmann DH, Tucker-Kellogg G, Ling SC. Peng AYT, et al. Among authors: agrawal i. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29101-29112. doi: 10.1073/pnas.2007806117. Epub 2020 Oct 30. Proc Natl Acad Sci U S A. 2020. PMID: 33127758 Free PMC article.
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
Ho WY, Chang JC, Lim K, Cazenave-Gassiot A, Nguyen AT, Foo JC, Muralidharan S, Viera-Ortiz A, Ong SJM, Hor JH, Agrawal I, Hoon S, Arogundade OA, Rodriguez MJ, Lim SM, Kim SH, Ravits J, Ng SY, Wenk MR, Lee EB, Tucker-Kellogg G, Ling SC. Ho WY, et al. Among authors: agrawal i. J Cell Biol. 2021 Sep 6;220(9):e201910213. doi: 10.1083/jcb.201910213. Epub 2021 Aug 4. J Cell Biol. 2021. PMID: 34347016 Free PMC article.
67 results