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Overcoming target epitope masking resistance that can occur on low-antigen-expresser AML blasts after IL-1RAP chimeric antigen receptor T cell therapy using the inducible caspase 9 suicide gene safety switch.
Warda W, Da Rocha MN, Trad R, Haderbache R, Salma Y, Bouquet L, Roussel X, Nicod C, Deschamps M, Ferrand C. Warda W, et al. Cancer Gene Ther. 2021 Dec;28(12):1365-1375. doi: 10.1038/s41417-020-00284-3. Epub 2021 Jan 7. Cancer Gene Ther. 2021. PMID: 33414517 Free PMC article.
CML Hematopoietic Stem Cells Expressing IL1RAP Can Be Targeted by Chimeric Antigen Receptor-Engineered T Cells.
Warda W, Larosa F, Neto Da Rocha M, Trad R, Deconinck E, Fajloun Z, Faure C, Caillot D, Moldovan M, Valmary-Degano S, Biichle S, Daguindau E, Garnache-Ottou F, Tabruyn S, Adotevi O, Deschamps M, Ferrand C. Warda W, et al. Cancer Res. 2019 Feb 1;79(3):663-675. doi: 10.1158/0008-5472.CAN-18-1078. Epub 2018 Dec 4. Cancer Res. 2019. PMID: 30514753
[IL-1RAP as a candidate for CAR T-cells immunotherapy].
Neto Da Rocha M, Trad R, Warda W, Haderbache R, Bouquet L, Nicod C, Deschamps M, Ferrand C. Neto Da Rocha M, et al. Among authors: warda w. Med Sci (Paris). 2019 Jun-Jul;35(6-7):497-500. doi: 10.1051/medsci/2019105. Epub 2019 Jul 5. Med Sci (Paris). 2019. PMID: 31274074 Free article. French. No abstract available.
CD28/4-1BB CD123 CAR T cells in blastic plasmacytoid dendritic cell neoplasm.
Bôle-Richard E, Fredon M, Biichlé S, Anna F, Certoux JM, Renosi F, Tsé F, Molimard C, Valmary-Degano S, Jenvrin A, Warda W, Pallandre JR, Bonnefoy F, Poussard M, Deschamps M, Petrella T, Roumier C, Macintyre E, Féger F, Brissot E, Mohty M, HoWangYin KY, Langlade-Demoyen P, Loustau M, Caumartin J, Godet Y, Binda D, Pagadoy M, Deconinck E, Daguindau E, Saas P, Ferrand C, Angelot-Delettre F, Adotévi O, Garnache-Ottou F. Bôle-Richard E, et al. Among authors: warda w. Leukemia. 2020 Dec;34(12):3228-3241. doi: 10.1038/s41375-020-0777-1. Epub 2020 Feb 28. Leukemia. 2020. PMID: 32111969
EZH2 and KDM6B Expressions Are Associated with Specific Epigenetic Signatures during EMT in Non Small Cell Lung Carcinomas.
Lachat C, Bruyère D, Etcheverry A, Aubry M, Mosser J, Warda W, Herfs M, Hendrick E, Ferrand C, Borg C, Delage-Mourroux R, Feugeas JP, Guittaut M, Hervouet E, Peixoto P. Lachat C, et al. Among authors: warda w. Cancers (Basel). 2020 Dec 5;12(12):3649. doi: 10.3390/cancers12123649. Cancers (Basel). 2020. PMID: 33291363 Free PMC article.
Droplet digital PCR allows vector copy number assessment and monitoring of experimental CAR T cells in murine xenograft models or approved CD19 CAR T cell-treated patients.
Haderbache R, Warda W, Hervouet E, da Rocha MN, Trad R, Allain V, Nicod C, Thieblemeont C, Boissel N, Varlet P, Agha IY, Bouquet L, Guiot M, Venet F, Sujobert P, Roussel X, Rouzaire PO, Caillot D, Casasnovas O, Bories JC, Bachy E, Caillat-Zucman S, Deschamps M, Ferrand C. Haderbache R, et al. Among authors: warda w. J Transl Med. 2021 Jun 21;19(1):265. doi: 10.1186/s12967-021-02925-z. J Transl Med. 2021. PMID: 34154602 Free PMC article.
Chimeric antigen receptor T-cells targeting IL-1RAP: a promising new cellular immunotherapy to treat acute myeloid leukemia.
Trad R, Warda W, Alcazer V, Neto da Rocha M, Berceanu A, Nicod C, Haderbache R, Roussel X, Desbrosses Y, Daguindau E, Renosi F, Roumier C, Bouquet L, Biichle S, Guiot M, Seffar E, Caillot D, Depil S, Robinet E, Salma Y, Deconinck E, Deschamps M, Ferrand C. Trad R, et al. Among authors: warda w. J Immunother Cancer. 2022 Jul;10(7):e004222. doi: 10.1136/jitc-2021-004222. J Immunother Cancer. 2022. PMID: 35803613 Free PMC article.
Coated recombinant target protein helps explore IL-1RAP CAR T-cell functionality in vitro.
Da Rocha MN, Guiot M, Nicod C, Trad R, Bouquet L, Haderbache R, Warda W, Baurand PE, Jouanneau C, Dulieu P, Deschamps M, Ferrand C. Da Rocha MN, et al. Among authors: warda w. Immunol Res. 2023 Apr;71(2):276-282. doi: 10.1007/s12026-022-09348-y. Epub 2022 Dec 2. Immunol Res. 2023. PMID: 36456721 Free PMC article. No abstract available.
13 results