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Page 1
The Orai Pore Opening Mechanism.
Tiffner A, Maltan L, Weiß S, Derler I. Tiffner A, et al. Int J Mol Sci. 2021 Jan 7;22(2):533. doi: 10.3390/ijms22020533. Int J Mol Sci. 2021. PMID: 33430308 Free PMC article. Review.
CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions.
Tiffner A, Schober R, Höglinger C, Bonhenry D, Pandey S, Lunz V, Sallinger M, Frischauf I, Fahrner M, Lindinger S, Maltan L, Berlansky S, Stadlbauer M, Schindl R, Ettrich R, Romanin C, Derler I. Tiffner A, et al. J Biol Chem. 2021 Jan-Jun;296:100224. doi: 10.1074/jbc.RA120.015548. Epub 2020 Dec 29. J Biol Chem. 2021. PMID: 33361160 Free PMC article.
Blockage of Store-Operated Ca2+ Influx by Synta66 is Mediated by Direct Inhibition of the Ca2+ Selective Orai1 Pore.
Waldherr L, Tiffner A, Mishra D, Sallinger M, Schober R, Frischauf I, Schmidt T, Handl V, Sagmeister P, Köckinger M, Derler I, Üçal M, Bonhenry D, Patz S, Schindl R. Waldherr L, et al. Among authors: tiffner a. Cancers (Basel). 2020 Oct 6;12(10):2876. doi: 10.3390/cancers12102876. Cancers (Basel). 2020. PMID: 33036292 Free PMC article.
Orai1 Boosts SK3 Channel Activation.
Tiffner A, Hopl V, Schober R, Sallinger M, Grabmayr H, Höglinger C, Fahrner M, Lunz V, Maltan L, Frischauf I, Krivic D, Bhardwaj R, Schindl R, Hediger MA, Derler I. Tiffner A, et al. Cancers (Basel). 2021 Dec 17;13(24):6357. doi: 10.3390/cancers13246357. Cancers (Basel). 2021. PMID: 34944977 Free PMC article.
13 results