Lopez M - Search Results

1

Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest.

Lobo J, Cardoso AR, Miranda-Gonçalves V, Looijenga LHJ, Lopez M, Arimondo PB, Henrique R, Jerónimo C. Lobo J, et al. Among authors: lopez m. Pharmaceutics. 2021 Jan 7;13(1):73. doi: 10.3390/pharmaceutics13010073. Pharmaceutics. 2021. PMID: 33430420 Free PMC article.

2

DNA Methyltransferase Inhibitors: Development and Applications.

Lopez M, Halby L, Arimondo PB. Lopez M, et al. Adv Exp Med Biol. 2016;945:431-473. doi: 10.1007/978-3-319-43624-1_16. Adv Exp Med Biol. 2016. PMID: 27826847 Review.

3

Natural Products and Chemical Biology Tools: Alternatives to Target Epigenetic Mechanisms in Cancers.

Lascano S, Lopez M, Arimondo PB. Lascano S, et al. Among authors: lopez m. Chem Rec. 2018 Dec;18(12):1854-1876. doi: 10.1002/tcr.201800133. Epub 2018 Dec 10. Chem Rec. 2018. PMID: 30537358 Review.

4

Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells.

Pechalrieu D, Dauzonne D, Arimondo PB, Lopez M. Pechalrieu D, et al. Among authors: lopez m. Eur J Med Chem. 2020 Jan 15;186:111829. doi: 10.1016/j.ejmech.2019.111829. Epub 2019 Nov 1. Eur J Med Chem. 2020. PMID: 31757526 Free article.

5

Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs.

Pechalrieu D, Assemat F, Halby L, Marcellin M, Yan P, Chaoui K, Sharma S, Chiosis G, Burlet-Schiltz O, Arimondo PB, Lopez M. Pechalrieu D, et al. Among authors: lopez m. ACS Chem Biol. 2020 Apr 17;15(4):952-961. doi: 10.1021/acschembio.9b00965. Epub 2020 Apr 6. ACS Chem Biol. 2020. PMID: 32191434 Free PMC article.

6

Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines.

Marques-Magalhães Â, Graça I, Miranda-Gonçalves V, Henrique R, Lopez M, Arimondo PB, Jerónimo C. Marques-Magalhães Â, et al. Among authors: lopez m. Biomed Pharmacother. 2021 Sep;141:111681. doi: 10.1016/j.biopha.2021.111681. Epub 2021 Jun 15. Biomed Pharmacother. 2021. PMID: 34139552 Free article.

7

The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor.

Luviano N, Lopez M, Gawehns F, Chaparro C, Arimondo PB, Ivanovic S, David P, Verhoeven K, Cosseau C, Grunau C. Luviano N, et al. Among authors: lopez m. Epigenetics Chromatin. 2021 Oct 26;14(1):48. doi: 10.1186/s13072-021-00422-7. Epigenetics Chromatin. 2021. PMID: 34702322 Free PMC article.

8

Inhibitors of DNA Methylation.

Lopez M, Gilbert J, Contreras J, Halby L, Arimondo PB. Lopez M, et al. Adv Exp Med Biol. 2022;1389:471-513. doi: 10.1007/978-3-031-11454-0_17. Adv Exp Med Biol. 2022. PMID: 36350520 Free article. Review.

9

Epidrugs as Promising Tools to Eliminate Plasmodium falciparum Artemisinin-Resistant and Quiescent Parasites.

Reyser T, Paloque L, Nguyen M, Augereau JM, Fuchter MJ, Lopez M, Arimondo PB, Hassell-Hart S, Spencer J, Di Stefano L, Benoit-Vical F. Reyser T, et al. Among authors: lopez m. Pharmaceutics. 2023 Oct 10;15(10):2440. doi: 10.3390/pharmaceutics15102440. Pharmaceutics. 2023. PMID: 37896200 Free PMC article.

10

3-Halo-3-nitro-aza/thioflavanones: DNMT inhibitors with a two-site binding mode in the hDNMT3A catalytic pocket.

Serhouni A, Calzaferri F, Bessina Y, van der Lee A, Arimondo PB, Louet M, Winum JY, Lopez M. Serhouni A, et al. Among authors: lopez m. Bioorg Med Chem. 2025 Feb 1;118:117988. doi: 10.1016/j.bmc.2024.117988. Epub 2024 Nov 28. Bioorg Med Chem. 2025. PMID: 39689413 Free article.

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