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Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL.
Sivinski J, Ambrose AJ, Panfilenko I, Zerio CJ, Machulis JM, Mollasalehi N, Kaneko LK, Stevens M, Ray AM, Park Y, Wu C, Hoang QQ, Johnson SM, Chapman E. Sivinski J, et al. Among authors: johnson sm. mBio. 2021 Jan 12;12(1):e02167-20. doi: 10.1128/mBio.02167-20. mBio. 2021. PMID: 33436430 Free PMC article.
A biochemical screen for GroEL/GroES inhibitors.
Johnson SM, Sharif O, Mak PA, Wang HT, Engels IH, Brinker A, Schultz PG, Horwich AL, Chapman E. Johnson SM, et al. Bioorg Med Chem Lett. 2014 Feb 1;24(3):786-9. doi: 10.1016/j.bmcl.2013.12.100. Epub 2014 Jan 2. Bioorg Med Chem Lett. 2014. PMID: 24418775
GroEL/ES inhibitors as potential antibiotics.
Abdeen S, Salim N, Mammadova N, Summers CM, Frankson R, Ambrose AJ, Anderson GG, Schultz PG, Horwich AL, Chapman E, Johnson SM. Abdeen S, et al. Among authors: johnson sm. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3127-3134. doi: 10.1016/j.bmcl.2016.04.089. Epub 2016 May 4. Bioorg Med Chem Lett. 2016. PMID: 27184767 Free article.
Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA).
Abdeen S, Kunkle T, Salim N, Ray AM, Mammadova N, Summers C, Stevens M, Ambrose AJ, Park Y, Schultz PG, Horwich AL, Hoang QQ, Chapman E, Johnson SM. Abdeen S, et al. Among authors: johnson sm. J Med Chem. 2018 Aug 23;61(16):7345-7357. doi: 10.1021/acs.jmedchem.8b00989. Epub 2018 Aug 14. J Med Chem. 2018. PMID: 30060666 Free PMC article.
Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections.
Washburn A, Abdeen S, Ovechkina Y, Ray AM, Stevens M, Chitre S, Sivinski J, Park Y, Johnson J, Hoang QQ, Chapman E, Parish T, Johnson SM. Washburn A, et al. Among authors: johnson sm, johnson j. Bioorg Med Chem Lett. 2019 Jul 1;29(13):1665-1672. doi: 10.1016/j.bmcl.2019.04.034. Epub 2019 Apr 24. Bioorg Med Chem Lett. 2019. PMID: 31047750 Free PMC article.
644 results