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Page 1
Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure-Properties Relationships of mPEGylated Small Agonists of TGR5 Receptor.
Hoguet V, Lasalle M, Maingot M, Dequirez G, Boulahjar R, Leroux F, Piveteau C, Herledan A, Biela A, Dumont J, Chávez-Talavera O, Belloy L, Duplan I, Hennuyer N, Butruille L, Lestavel S, Sevin E, Culot M, Gosselet F, Staels B, Deprez B, Tailleux A, Charton J. Hoguet V, et al. Among authors: butruille l. J Med Chem. 2021 Feb 11;64(3):1593-1610. doi: 10.1021/acs.jmedchem.0c01774. Epub 2021 Jan 20. J Med Chem. 2021. PMID: 33470812
The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids.
Ducastel S, Touche V, Trabelsi MS, Boulinguiez A, Butruille L, Nawrot M, Peschard S, Chávez-Talavera O, Dorchies E, Vallez E, Annicotte JS, Lancel S, Briand O, Bantubungi K, Caron S, Bindels LB, Delzenne NM, Tailleux A, Staels B, Lestavel S. Ducastel S, et al. Among authors: butruille l. Sci Rep. 2020 Jan 13;10(1):174. doi: 10.1038/s41598-019-56743-x. Sci Rep. 2020. PMID: 31932631 Free PMC article.
PPAR control of metabolism and cardiovascular functions.
Montaigne D, Butruille L, Staels B. Montaigne D, et al. Among authors: butruille l. Nat Rev Cardiol. 2021 Dec;18(12):809-823. doi: 10.1038/s41569-021-00569-6. Epub 2021 Jun 14. Nat Rev Cardiol. 2021. PMID: 34127848 Review.
Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis.
Dehondt H, Marino A, Butruille L, Mogilenko DA, Nzoussi Loubota AC, Chávez-Talavera O, Dorchies E, Vallez E, Haas J, Derudas B, Bongiovanni A, Tardivel M, Kuipers F, Lefebvre P, Lestavel S, Tailleux A, Dombrowicz D, Caron S, Staels B. Dehondt H, et al. Among authors: butruille l. Mol Metab. 2023 Mar;69:101686. doi: 10.1016/j.molmet.2023.101686. Epub 2023 Feb 4. Mol Metab. 2023. PMID: 36746333 Free PMC article.
Diabetes mellitus and cardiovascular mortality across the spectrum of aortic stenosis.
Coisne A, Montaigne D, Ninni S, Lamblin N, Lemesle G, Delsart P, Filiot A, Andrey P, Balaye P, Butruille L, Decoin R, Woitrain E, Granada JF, Staels B, Bauters C; VALVENOR investigators. Coisne A, et al. Among authors: butruille l. Heart. 2022 Oct 28;108(22):1815-1821. doi: 10.1136/heartjnl-2022-320897. Heart. 2022. PMID: 35697496
High liver fibrosis scores in metabolic dysfunction-associated fatty liver disease patients are associated with adverse atrial remodeling and atrial fibrillation recurrence following catheter ablation.
Decoin R, Butruille L, Defrancq T, Robert J, Destrait N, Coisne A, Aghezzaf S, Woitrain E, Gouda Z, Schino S, Klein C, Maboudou P, Brigadeau F, Klug D, Vincentelli A, Dombrowicz D, Staels B, Montaigne D, Ninni S. Decoin R, et al. Among authors: butruille l. Front Endocrinol (Lausanne). 2022 Aug 31;13:957245. doi: 10.3389/fendo.2022.957245. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36120456 Free PMC article.
Heat-based transdermal delivery of a ramipril loaded cream for treating hypertension.
Voronova A, Pagneux Q, Decoin R, Woitrain E, Butruille L, Barras A, Foulon C, Lecoeur M, Jaramillo D, Rumipamba J, Melinte S, Abderrahmani A, Montaigne D, Boukherroub R, Szunerits S. Voronova A, et al. Among authors: butruille l. Nanoscale. 2022 Sep 2;14(34):12247-12256. doi: 10.1039/d2nr02295h. Nanoscale. 2022. PMID: 36000238
Reduced PPARγ2 expression in adipose tissue of male rat offspring from obese dams is associated with epigenetic modifications.
Lecoutre S, Pourpe C, Butruille L, Marousez L, Laborie C, Guinez C, Lesage J, Vieau D, Eeckhoute J, Gabory A, Oger F, Eberlé D, Breton C. Lecoutre S, et al. Among authors: butruille l. FASEB J. 2018 May;32(5):2768-2778. doi: 10.1096/fj.201700997R. Epub 2018 Jan 8. FASEB J. 2018. PMID: 29295860
Consistent with the DOHaD hypothesis, retained epigenetic marks provide a mechanistic basis for the cellular memory linking maternal obesity to a predisposition for later adiposity.-Lecoutre, S., Pourpe, C., Butruille, L., Marousez, L., Laborie, C., Guinez, C …
Consistent with the DOHaD hypothesis, retained epigenetic marks provide a mechanistic basis for the cellular memory linking maternal obesity …
52 results