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Nonclinical Safety Assessment of AMG 553, an Investigational Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Acute Myeloid Leukemia.
Karbowski C, Goldstein R, Frank B, Kim K, Li CM, Homann O, Hensley K, Brooks B, Wang X, Yan Q, Hernandez R, Adams G, Boyle M, Arvedson T, Lebrec H. Karbowski C, et al. Among authors: homann o. Toxicol Sci. 2020 Sep 1;177(1):94-107. doi: 10.1093/toxsci/kfaa098. Toxicol Sci. 2020. PMID: 32589753 Free PMC article.
RAB18 regulates extrahepatic siRNA-mediated gene silencing efficacy.
Lu J, Lee J, Yuan E, Wakefield DL, Kanke M, Pruitt D, Barreda J, Rulifson IC, Xie J, Ferbas J, Long J, Meade B, Homann O, Guo W, Gomes T, Zhou H, Wu B, Cui J, Wang S. Lu J, et al. Among authors: homann o. Mol Ther Nucleic Acids. 2024 Sep 10;35(4):102335. doi: 10.1016/j.omtn.2024.102335. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39380712 Free PMC article.
AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer.
Giffin MJ, Cooke K, Lobenhofer EK, Estrada J, Zhan J, Deegen P, Thomas M, Murawsky CM, Werner J, Liu S, Lee F, Homann O, Friedrich M, Pearson JT, Raum T, Yang Y, Caenepeel S, Stevens J, Beltran PJ, Canon J, Coxon A, Bailis JM, Hughes PE. Giffin MJ, et al. Among authors: homann o. Clin Cancer Res. 2021 Mar 1;27(5):1526-1537. doi: 10.1158/1078-0432.CCR-20-2845. Epub 2020 Nov 17. Clin Cancer Res. 2021. PMID: 33203642
21 results