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NmeCas9 is an intrinsically high-fidelity genome-editing platform.
Amrani N, Gao XD, Liu P, Edraki A, Mir A, Ibraheim R, Gupta A, Sasaki KE, Wu T, Donohoue PD, Settle AH, Lied AM, McGovern K, Fuller CK, Cameron P, Fazzio TG, Zhu LJ, Wolfe SA, Sontheimer EJ. Amrani N, et al. Among authors: liu p. Genome Biol. 2018 Dec 5;19(1):214. doi: 10.1186/s13059-018-1591-1. Genome Biol. 2018. PMID: 30518407 Free PMC article.
The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans.
Peterson ND, Cheesman HK, Liu P, Anderson SM, Foster KJ, Chhaya R, Perrat P, Thekkiniath J, Yang Q, Haynes CM, Pukkila-Worley R. Peterson ND, et al. Among authors: liu p. PLoS Genet. 2019 Jan 22;15(1):e1007935. doi: 10.1371/journal.pgen.1007935. eCollection 2019 Jan. PLoS Genet. 2019. PMID: 30668573 Free PMC article.
Enhanced Cas12a editing in mammalian cells and zebrafish.
Liu P, Luk K, Shin M, Idrizi F, Kwok S, Roscoe B, Mintzer E, Suresh S, Morrison K, Frazão JB, Bolukbasi MF, Ponnienselvan K, Luban J, Zhu LJ, Lawson ND, Wolfe SA. Liu P, et al. Nucleic Acids Res. 2019 May 7;47(8):4169-4180. doi: 10.1093/nar/gkz184. Nucleic Acids Res. 2019. PMID: 30892626 Free PMC article.
Genome-wide detection and analysis of CRISPR-Cas off-targets.
Rodríguez TC, Dadafarin S, Pratt HE, Liu P, Amrani N, Zhu LJ. Rodríguez TC, et al. Among authors: liu p. Prog Mol Biol Transl Sci. 2021;181:31-43. doi: 10.1016/bs.pmbts.2021.01.012. Epub 2021 Mar 4. Prog Mol Biol Transl Sci. 2021. PMID: 34127199
Genome-wide detection of CRISPR editing in vivo using GUIDE-tag.
Liang SQ, Liu P, Smith JL, Mintzer E, Maitland S, Dong X, Yang Q, Lee J, Haynes CM, Zhu LJ, Watts JK, Sontheimer EJ, Wolfe SA, Xue W. Liang SQ, et al. Among authors: liu p. Nat Commun. 2022 Jan 21;13(1):437. doi: 10.1038/s41467-022-28135-9. Nat Commun. 2022. PMID: 35064134 Free PMC article.
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